Protein Alignment Spn43Ab and SERPINB10

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_005015.1
• Gene: SERPINB10 / 5273
• HGNCID: 8942
• Length: 397
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 98/397 - (24%)
• Similarity: 183/397 - (46%)
• Gaps: 38/397 - (9%)

  Fly    26 AADRNLLAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPG-----D 85
            |...|..|.:|...:|.....:|:..|..:|.:|:.:.::||||.||:::.|.|:....     |
Human     5 ATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCD 69

  Fly    86 ADAVSQRS------------GSYQQALTR------DNNFRLANNIYINENLEFKGSFRDVAQRQF 132
            .::..:|.            ..:|..::.      |...:.||.||..:...|...:.:..:..|
Human    70 PESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKTYF 134

  Fly   133 DSNIDKLDFHPPYNKRTADGINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFR 197
            .:....::|....::...| ||..|..:|.|||.::|..:.::..|..::||.:.:...|:..|.
Human   135 GAEPQPVNFVEASDQIRKD-INSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFL 198

  Fly   198 LDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRS 262
            :..|.::.||.....|..|..|:..:..:...:....|..::|.|::.|.|:|:|||...:||..
Human   199 VQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDINGLEQ 263

  Fly   263 LQQSLSGKNLLAEIGA--MSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRD-GDFGNM--- 321
            |:::::.:.|.....|  |...:|::.||||.:.....|:.....:|:...||:. .||..|
Human   264 LEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSA 328

  Fly   322 YRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSR--SKKFEADHPFVFAIKYK--DSIA 382
            ..:|:|:    |.|||.||:.|.|.:....:|....:..|  |.:|.|:|||:|.|::.  ::|.
Human   329 RNLFLSN----VFHKAFVEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTIL 389

  Fly   383 FIGHIAN 389
            |.|.:.:
Human   390 FYGRLCS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	97/396 (24%)
SERPINB10	NP_005015.1	serpinB10_bomapin	1..397	CDD:381035	98/397 (25%)
		Nuclear localization signal	74..77		0/2 (0%)