Protein Alignment Spn43Ab and SERPINB5

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 102/369 - (27%)
• Similarity: 174/369 - (47%)
• Gaps: 26/369 - (7%)

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQ 97
            |.||:..:.......||:.||..:.:|::||.|||||.||:|:.|.|..     :.|......:
Human    12 AVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF-----ENVKDVPFGF- 70

  Fly    98 QALTRDNN-------FRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINR 155
            |.:|.|.|       .:|...:|::::|.....|....:|.:...::.:||.... :.|...||.
Human    71 QTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKL-EETKGQINN 134

  Fly   156 AVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMW 220
            ::...|:|...:||....:||:|:.::||...:...|.|.|...:|::..||.....:..|..|.
Human   135 SIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMN 199

  Fly   221 TLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLP----NRKDGLRSLQQSLSGKNL--LAEIGAM 279
            ....|....::|::.|::|||:||...||.:|||    :...||..:::.|:.::|  ......|
Human   200 MEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTM 264

  Fly   280 SQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRD-GDFGNMYRMFVSHFINAVEHKANVEVTE 343
            :..||::.:|||.|...:..:...:.||:..:||.| .||..|.........|.: ||..:|:||
Human   265 ANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVI-HKVCLEITE 328

  Fly   344 AGVDQPLETGLLKGLFSRSKKFEADHPFVFAIKYKD--SIAFIG 385
            .|.|.....|  ..:.....:..|||||::.|::..  :|.|.|
Human   329 DGGDSIEVPG--ARILQHKDELNADHPFIYIIRHNKTRNIIFFG 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	102/369 (28%)
SERPINB5	NP_002630.2	serpinB5_maspin	1..375	CDD:381013	102/369 (28%)