Protein Alignment Spn43Ab and SERPINA1

DIOPT Version :9

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 88/365 - (24%)
• Similarity: 158/365 - (43%)
• Gaps: 16/365 - (4%)

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQ 97
            |..||..:|....:.|:..||.:|.::.|:..:|.|..|..|:.:||.....:........| :|
Human    58 AFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG-FQ 121

  Fly    98 QALTR----DNNFRL--ANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRA 156
            :.|..    |:..:|  .|.::::|.|:....|.:..::.:.|....::|..  .:.....||..
Human   122 ELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGD--TEEAKKQINDY 184

  Fly   157 VATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWT 221
            |...|.|||.|::: ||..| |...:||.:.:...|::.|.:..||:..|......:|||..|..
Human   185 VEKGTQGKIVDLVK-ELDRD-TVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247

  Fly   222 LQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLAEIGAMSQQKVEV 286
            |..||......|.:.|:.:.|.. :.:.:..||: :..|:.|:..|:...:...:....::...:
Human   248 LGMFNIQHCKKLSSWVLLMKYLG-NATAIFFLPD-EGKLQHLENELTHDIITKFLENEDRRSASL 310

  Fly   287 LLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLE 351
            .|||.|:|....|:....:||:..:||...|...:..........|| |||.:.:.|.|.:....
Human   311 HLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAV-HKAVLTIDEKGTEAAGA 374

  Fly   352 TGLLKGLFSRSKKFEADHPFVFAI--KYKDSIAFIGHIAN 389
            ..|.....|...:.:.:.||||.:  :...|..|:|.:.|
Human   375 MFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	87/361 (24%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	87/361 (24%)
		RCL	368..392		3/23 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010