Protein Alignment Spn43Ab and SERPINA5

DIOPT Version :9

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 99/379 - (26%)
• Similarity: 178/379 - (46%)
• Gaps: 32/379 - (8%)

  Fly    25 AAADRNLLAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAV 89
            |.:.|.....|||.|:|:...::::..||.:|..|:|:..:||...|..::.:||.|....:...
Human    41 APSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEK 105

  Fly    90 SQRSGSYQQALTRDNNFR------LANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKR 148
            ....| :||.|...|..|      |.|.::.:..::.:.:|....:..:.::..      |.|.|
Human   106 ELHRG-FQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTF------PTNFR 163

  Fly   149 TADG----INRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTG 209
            .:.|    ||..||.:|.|||.|:|:.  |:.....::||.:.:.|.|:.:|....|:::.|...
Human   164 DSAGAMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 226

  Fly   210 SGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLA 274
            |...|:|..|.....::|....:|..:||.:|||. :.:.|.:||: :..::.::..||.|.|..
Human   227 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQG-NATALFILPS-EGKMQQVENGLSEKTLRK 289

  Fly   275 EIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGD---FGNMYRMFVSHFINAVEHK 336
            .:....::::|:.|||||:.....||.....||:..:|:...|   ..|...:.||..:    ||
Human   290 WLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMV----HK 350

  Fly   337 ANVEVTEAGVDQPLETGLL---KGLFSRSKKFEADHPFVFAIKYKDSIAFIGHI 387
            |.|||.|:|......||.:   :.....|::...:.||:..| ..::|.|:|.:
Human   351 AVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI-VDNNILFLGKV 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	97/372 (26%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	98/374 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010