Protein Alignment Spn43Ab and SERPINC1

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 92/420 - (21%)
• Similarity: 184/420 - (43%)
• Gaps: 99/420 - (23%)

  Fly    46 NENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGS-------------YQ 97
            |:|:.:||.:|.::.|:..:||...|..:|.:..:.     |.:|:::..             |:
Human   105 NDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKF-----DTISEKTSDQIHFFFAKLNCRLYR 164

  Fly    98 QALTRDNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTAD----GINRAVA 158
            :| .:.:....||.::.:::|.|..:::|:::..:.:.:..|||     |..|:    .||:.|:
Human   165 KA-NKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDF-----KENAEQSRAAINKWVS 223

  Fly   159 TKTNGKITDILRAELLNDRTEGVIVNGVSY----------------------------------- 188
            .||.|:|||::.:|.:|:.|..|:||.:.:
Human   224 NKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERAN 288

  Fly   189 ------SAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDF 247
                  ...|:..|..:.|.|..|....|:|.....|:....|.|..| :...:|:|||::..|.
Human   289 GLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRV-AEGTQVLELPFKGDDI 352

  Fly   248 SMLLLLPNRKDGLRSLQQSLSGKNLLAEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMF 312
            :|:|:||..:..|..:::.|:.:.|...:..:.:..:.|.:|:|.:..|..|:...:.:|:..:|
Human   353 TMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLF 417

  Fly   313 S-------------RDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLL---KGLFSR 361
            |             ||    ::|       ::...|||.:||.|.|.:....|.::   :.|...
Human   418 SPEKSKLPGIVAEGRD----DLY-------VSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPN 471

  Fly   362 SKKFEADHPFVFAIKY--KDSIAFIGHIAN 389
            ...|:|:.||:..|:.  .::|.|:|.:||
Human   472 RVTFKANRPFLVFIREVPLNTIIFMGRVAN 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	92/420 (22%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	92/420 (22%)