DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinb6e

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001039000.2	Gene:	Serpinb6e / 435350	MGIID:	2667778	Length:	429	Species:	Mus musculus

Alignment Length:	412	Identity:	116/412 - (28%)
Similarity:	193/412 - (46%)	Gaps:	43/412 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IISCLLLLLATVSQSKTVGYDAAADRN-LLAADLYNAVAADHLNENVVISPATIQSSMALAFVGA 67
            |:.|:.::|..:..|:....|:..:.| .....|:..:..|. ::||..|.:::.||:||..:||
Mouse    34 ILDCVFIMLIVILHSRYTIMDSLLEANATFTLKLFRVLGEDS-SKNVFFSSSSMFSSLALILMGA 97

  Fly    68 KGQTASELQQGLRL---GPGDADAVSQRSGSYQQALTRDNN------FRLANNIYINENLEFKGS 123
            .|.|||::.|.|.|   ..|.|| |.|   .:|..||..|.      .|.||.|:.:.|.:...|
Mouse    98 NGTTASQISQVLSLDKCSNGGAD-VQQ---GFQSLLTEVNKTDTGHMLRRANKIFSDNNFDIMES 158

  Fly   124 FRDVAQRQFDSNIDKLDFHPPYNKRTAD----GINRAVATKTNGKITDILRAELLNDRTEGVIVN 184
            |::...:.:...|:||||     |.|.:    .||..||.||...|.::|....:|..|..::||
Mouse   159 FKESCYKLYRVEIEKLDF-----KGTPEQCRQHINAWVAKKTKDVIRELLSLYTVNSNTRLILVN 218

  Fly   185 GVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFN--YAEVNSLDAKVVELPYQNPDF 247
            ...:...|:|.|..:.|.:..|:....:...|..|.....|.  |||  .:...:|.|||.:.:.
Mouse   219 ATYFKGKWEKQFNKEDTREMPFKVSKNEKKTVQMMSKKSTFKTYYAE--EISTTIVFLPYTDKEL 281

  Fly   248 SMLLLLPNRKDGLRSLQQSLSGKNLL--AEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHT 310
            ||:::||:.:..|..::..:|.|.|:  ..:..|.:::|:|.||:|.:.....::....|||:..
Mouse   282 SMIIMLPDEQVELSMVENQISYKKLIQWTRLVKMEEEEVQVFLPRFKLEATYDMKDVLCKLGMTD 346

  Fly   311 MFSRD-GDFGNMYRMFVSH----FINAVEHKANVEVTEAGVDQPLETGLLK-GLFSRSKKFEADH 369
            .|... .||..     :|.    |::.|.||:.|||.|.|.:..:.|.::. |.....:...||.
Mouse   347 AFEESRADFSG-----ISSKKGLFLSNVVHKSFVEVNEEGTEAAVATEIVTVGSPLTQRCLIADR 406

  Fly   370 PFVFAIKYKDS--IAFIGHIAN 389
            ||:|.|:...|  |.|:|..::
Mouse   407 PFLFLIQGDKSKEILFLGRFSS 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	111/382 (29%)
Serpinb6e	NP_001039000.2	serpin	53..429	CDD:393296	112/393 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930