DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpina11

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001008776.1	Gene:	Serpina11 / 362774	RGDID:	1359239	Length:	462	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	100/463 - (21%)
Similarity:	189/463 - (40%)	Gaps:	84/463 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VIISCLLLLL----ATVSQSKTVGY-DAAADRNLLAADLYNAVA--------------ADHLNEN 48
            ::|:.|||.:    ::....|::|. ..|:.::|..|..|:.|.              |:.:..|
  Rat     8 LLIAELLLPVHYQPSSAHGDKSLGAPQPASHQSLEPAPAYHKVTPTITNFALRLYKQLAEEIPGN 72

  Fly    49 VVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQQALTRD-----NNFRL 108
            ::.||.::.|::||..:||...|.:::.|.|.....:..|.....|......|.|     ...:|
  Rat    73 ILFSPVSLSSTVALLSLGAHADTQAQILQSLGFNLTETPAADIHRGFQSLLHTLDLPSPKLELKL 137

  Fly   109 ANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADG--INRAVATKTNGKITDILRA 171
            .::::::..|:.:..|.|.|:..:.:    |.|...:.:..|.|  ||..|..:|.|::...| .
  Rat   138 GHSLFLDRQLKPQQRFLDSAKELYGA----LAFSANFTEAAATGQQINDLVRKQTYGQVVGCL-P 197

  Fly   172 ELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKR-SFRTGSGQSVKVDTMWTLQNFNYAEVNSLDA 235
            |...| |..|::|.:.:.|.|:..|...:|.|: ||.......:::..|...:...:........
  Rat   198 EFDRD-TLMVLLNYIFFKAKWKHPFDRYQTRKQESFFVDQRLQLRIPMMRQKEMHRFLYDQEASC 261

  Fly   236 KVVELPYQNPDFSMLLLLPN-------------------------RK-------------DGLRS 262
            .|:::.|..... :||:||:                         ||             |.:..
  Rat   262 TVLQIEYSGTAL-LLLVLPDPGKMQQVEAALQPETLRRWGQRFLPRKAQAGGAGNGGLHWDRVNE 325

  Fly   263 LQQSLSGKNLLAEIGAMSQ--QKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMF 325
            ..|:..||..|..: .|:|  ..:::.||:|||:....||.....:|:.::|..:.|...:...
  Rat   326 FPQNRVGKLSLKHL-QMTQTWSLLDLHLPRFSVSATYNLEEILPLVGLSSLFDVEADLSGIMGQ- 388

  Fly   326 VSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSRSKKFEADH-----PFVFAI--KYKDSIAF 383
            ::..::.|.|||.|::.|.|.:....:|||....|.:.. .|.|     ||:..:  ....|:.|
  Rat   389 LNKTVSRVSHKAVVDMNEKGTEAAAASGLLSQPPSLNMT-SAPHAHFNRPFLLLLWEVTTQSLLF 452

  Fly   384 IGHIANYA 391
            :|.:.|.|
  Rat   453 LGKVVNPA 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	91/425 (21%)
Serpina11	NP_001008776.1	alpha-1-antitrypsin_like	53..456	CDD:239011	87/412 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010