DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinb9

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	XP_006253934.1	Gene:	Serpinb9 / 361241	RGDID:	1549730	Length:	396	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	105/400 - (26%)
Similarity:	188/400 - (47%)	Gaps:	39/400 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CLLLLLATVSQSKTVGYDAAADRNLLAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQT 71
            |.|.::.|:|::          ....|..|...:...:.:|||..||.:|.|::|:..:||||||
  Rat    18 CRLCIMNTLSEA----------NGTFAIHLLKMLCQSNPSENVCYSPVSISSALAMVLLGAKGQT 72

  Fly    72 ASELQQGLRLGPGDADAVSQRSGSYQQALT------RDNNFRLANNIYINENLEFKGSFRDVAQR 130
            ..::.|.|.|     :........:|..|:      |..:.|:||.::.::..|...::::...|
  Rat    73 QVQISQALGL-----NKEKDLHQGFQLLLSNLNKPERKYSLRVANRLFADKTCELLPTYKESCLR 132

  Fly   131 QFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKA 195
            .::|.:::|.| ....:.:...||..|:.:|.|||.::|....::..|..|:||.:.:...|.:.
  Rat   133 FYNSEMEQLSF-AEAAEESRKHINTWVSKQTEGKIPELLSGGSVDSETRLVLVNALYFKGRWHQP 196

  Fly   196 FRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGL 260
            |..:.|....|:....:...|..|.....:|.|.|..:.|:|:.:||:..:.|.::|||:....|
  Rat   197 FNKEYTVDMPFKINKNEKRLVQMMCCEDTYNLAHVKEVQAQVLMMPYEGMELSFVVLLPDNDGDL 261

  Fly   261 RSLQQSLSGKNLLAEIGA--MSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSR-DGDFGNM- 321
            ..::.:|:.:.|.|....  |....|||.||||.:.....:|..|::||:..:|.. ..|...|
  Rat   262 SKVESNLTFEKLTAWTNPDFMKNTNVEVFLPKFKLQEDYDMESVFQRLGIVDVFQEAKADLSAMS 326

  Fly   322 --YRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLK---GLFSRSKKFEADHPFVFAIKYK--D 379
              ..:.||..:    ||:.|||.|.|.:....:.:::   ..|..:  |.|||||:|.||:.  :
  Rat   327 PERNLCVSKIV----HKSLVEVNEEGTEAAAASAVIEYCCAAFVPT--FCADHPFLFFIKHNKTN 385

  Fly   380 SIAFIGHIAN 389
            ||.|.|..::
  Rat   386 SILFCGRFSS 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	101/373 (27%)
Serpinb9	XP_006253934.1	SERPIN	26..396	CDD:294093	102/391 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930