DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and serpinb1l3

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	XP_005174262.1	Gene:	serpinb1l3 / 335119	ZFINID:	ZDB-GENE-030131-7059	Length:	415	Species:	Danio rerio

Alignment Length:	419	Identity:	114/419 - (27%)
Similarity:	197/419 - (47%)	Gaps:	46/419 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AVIISCLLLLLATVS-------QSKTVGYDAAADRNLLAADLYNAVAADHLNENVVISPATIQSS 59
            |.|..||.|..|..:       .|:.....||..|..|:  |:..::....::||..||.:|.::
Zfish    11 AHITRCLRLHTACGTPPTEDSCSSRMEPLSAAHARFCLS--LFQKISDGDSSQNVFFSPLSISAA 73

  Fly    60 MALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQQALTRDN------NFRLANNIYINENL 118
            :::..:||.|.|..::.|.|...    .|.||....:.:.||..|      ...||:.:|..::.
Zfish    74 LSMLSLGAAGNTKDQMSQTLHFD----GAESQIHAGFTKLLTEMNRAGAPHTLSLASRLYGEQSC 134

  Fly   119 EFKGSFRDVAQRQFDSNIDKLDF-HPPYNKRTADGINRAVATKTNGKITDILRAELLNDRTEGVI 182
            .|:.:|....:|.:.:.:..||| ..|...|..  |||.|..:|:.||.|:|....::..:..|:
Zfish   135 RFQETFLSDTRRLYGAELQPLDFISQPEASRGI--INRWVEQQTHEKIRDLLAEGSVDSLSRLVL 197

  Fly   183 VNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDF 247
            ||.|.:.::|::.|..:.|.::.|||...:|..|..|:....|..|.:..::.:::||||...:.
Zfish   198 VNAVYFKSSWERKFLEEHTHEQQFRTSRNESKPVQMMFQKGRFPLAFIPDVNCQILELPYAGKEL 262

  Fly   248 SMLLLLPNRKD----GLRSLQQSLSGKNLL--AEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKL 306
            |||:||||..:    ||..|:::|:.:.|.  .....|...:|||.||:..|...|.|:....:|
Zfish   263 SMLVLLPNAMEDDGTGLEKLERALTLETLTDWTRSDMMDVLEVEVSLPRLRVEERLELKPLLVEL 327

  Fly   307 GVHTMFS-RDGDF------GNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETG--LLKGLFSRS 362
            |:...|. :..||      |.:       .::.|.|::.:||.|.|.:....|.  ::.....|:
Zfish   328 GMPDAFDPQRADFSGVCAGGEL-------LLSTVVHQSFLEVNEEGTEAAAATAAVMMTRCLMRA 385

  Fly   363 KKFEADHPFVFAIKYK--DSIAFIGHIAN 389
            ::|.|||||:..|::.  .|:.|.|.:.|
Zfish   386 ERFCADHPFLMLIRHNPTGSLLFYGRVCN 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	103/380 (27%)
serpinb1l3	XP_005174262.1	SERPIN	39..415	CDD:294093	107/391 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930