DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001100821.1	Gene:	Serpinb9d / 306890	RGDID:	1308725	Length:	337	Species:	Rattus norvegicus

Alignment Length:	345	Identity:	88/345 - (25%)
Similarity:	166/345 - (48%)	Gaps:	26/345 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQQALTRDNN------FRLANNIYINENLEF 120
            :..:||||.||.::.|.|.|.....:.:.:   .:|..|...|.      .|:||.::.....:.
  Rat     1 MVLLGAKGDTAVQISQALNLNKHPDEDIHK---DFQLLLHNLNKPKSHYCLRIANRLFAENTCKL 62

  Fly   121 KGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKITDILRAELLNDRTEGVIVNG 185
            ..::::...|.::|.|::|.| ....:.:...||..|:.:|.|||.::|.::.:...|:.::||.
  Rat    63 VPTYKESCLRFYNSEIEQLSF-AKAAEESRKHINTWVSKQTEGKIPELLSSDSVGSETKLIMVNA 126

  Fly   186 VSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSML 250
            :.:..:|...|..:.|.:..|:....::..|..||..:.|:.|.|..:.|:::.:||:..:.|.:
  Rat   127 LYFQGSWLHCFDKEFTMEMPFKINKKETKPVQMMWQEETFDVAYVKEIQAQILVMPYRGMEMSFM 191

  Fly   251 LLLPNRKDGLRSLQQSLSGKNLLA--EIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFS 313
            :|||:....:|.::.||:.:.|.|  :...:...:|.|.||||.:.....:...|:.||:..:||
  Rat   192 VLLPDEGVDIRKVESSLTFEKLTAWTKPEFIYSTEVYVYLPKFQLQEQYDMTALFQHLGMIDVFS 256

  Fly   314 R-DGDFGNM---YRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSRSK---KFEADHPF 371
            . ..|...|   ..:.||.|:    |:..|||.|.|.:....:. ....:|.|:   .|.||.||
  Rat   257 EIKADLSGMCPEKDLCVSKFV----HECVVEVNEEGTEAAAASA-ADCCYSCSEYTPTFCADRPF 316

  Fly   372 VFAIKYK--DSIAFIGHIAN 389
            :|.|::.  :||.|.|..::
  Rat   317 LFFIRHNQTNSILFCGRFSS 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	88/341 (26%)
Serpinb9d	NP_001100821.1	SERPIN	1..337	CDD:294093	88/345 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930