Protein Alignment Spn43Ab and SERPIND1

DIOPT Version :9

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_000176.2
• Gene: SERPIND1 / 3053
• HGNCID: 4838
• Length: 499
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 104/390 - (26%)
• Similarity: 181/390 - (46%)
• Gaps: 51/390 - (13%)

  Fly    30 NLL----AADLYNAVAADHLN--ENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADA 88
            |:|    |.:||. |..|.:|  :|:.|:|..|.::|.:..:|.||:|..::...|..    .|.
Human   127 NILNAKFAFNLYR-VLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHF----KDF 186

  Fly    89 VSQRSGSYQ------------QALTRDN---NFRLANNIYINEN----LEFKGSFRD--VAQRQF 132
            |: .|..|:            ..|.|.|   ..|..|::||.:.    |:||...|:  .|:.|.
Human   187 VN-ASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQI 250

  Fly   133 DSNIDKLDF-HPPYNKRTADGINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAF 196
                  .|| .|.:..:|    |..:...|.|.|.|.|  |.::..|:.:|:|.:.:..:|...|
Human   251 ------ADFSDPAFISKT----NNHIMKLTKGLIKDAL--ENIDPATQMMILNCIYFKGSWVNKF 303

  Fly   197 RLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLR 261
            .::.|...:||....:.|||..|.|..||..|....||..:::|.|.. ..|||:::|::..|::
Human   304 PVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GISMLIVVPHKMSGMK 367

  Fly   262 SLQQSLSGKNLLAEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFV 326
            :|:..|:.:.:.....:|:.:..|||||||.:.....|....|.:|:..:|.::|:...:....:
Human   368 TLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQRI 432

  Fly   327 SHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSRSKKFEADHPFVFAI-KYKDS-IAFIGHIAN 389
            :  |:..:|:..:.|.|.|......|.:.....|...:|..|.||:|.| :::.| :.|:|.:||
Human   433 A--IDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFMGRVAN 495

  Fly   390  389
            Human   496  495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	102/386 (26%)
SERPIND1	NP_000176.2	HCII	62..497	CDD:239002	104/390 (27%)
		Chemotactic activity	68..79
		2 X 11 AA approximate repeats, Asp/Glu-rich (acidic) (hirudin-like)	73..97
		Glycosaminoglycan-binding site	192..212		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020