DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and LOC299277

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	XP_008763124.2	Gene:	LOC299277 / 299277	RGDID:	1595900	Length:	420	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	83/331 - (25%)
Similarity:	145/331 - (43%)	Gaps:	22/331 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQ 97
            |..||..:|..:.|:|:..||.:|.:::|...:||||.|..|:.:||:....:...:.... :|:
  Rat    55 AFSLYKELALKNPNKNIAFSPLSISAALASLSLGAKGNTLQEILEGLKFNLTETTEIDIHQ-NYR 118

  Fly    98 QALTR------DNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRA 156
            ..|.|      ......||.:::.::|:....|::.|:..:.:.:...||......|..  ||..
  Rat   119 DLLQRLSQPGGQGQISRANLLFVEKHLQILNGFKEKAKALYQTEVFATDFQQTCEARKF--INDY 181

  Fly   157 VATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWT 221
            |..::.|||.:::..  |.:||..|::|.:.::..|...|..|.|....|...|.:.|||..|.|
  Rat   182 VMIQSQGKIKEMVTE--LEERTSIVMLNFLLFTGQWSVPFDPDDTFMGKFILDSRRPVKVLMMKT 244

  Fly   222 LQ-NFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLAEIGAMSQQKVE 285
            .. ...|.....|...||||.|:....:|.:|....|  :..::.||....|.....::..:.::
  Rat   245 EDLTTPYFWDEELKCTVVELNYKGHGKAMFILPDQGK--MEQVEASLHPGTLRKWTDSLKPRIID 307

  Fly   286 VL-LPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNM---YRMFVSHFINAVEHKANVEVTEAGV 346
            .| |||||::....||....:||:..:|:...|...:   ..:.||..|    |...:.:.|.|.
  Rat   308 ELHLPKFSLSKTYKLENILPELGIMDVFNTQADLSGIAGAKDVRVSQMI----HNTVLGMAETGT 368

  Fly   347 DQPLET 352
            :....|
  Rat   369 EAEATT 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	83/331 (25%)
LOC299277	XP_008763124.2	serpinA3_A1AC	37..417	CDD:381019	83/331 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100