DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinb1a

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001026812.1	Gene:	Serpinb1a / 291091	RGDID:	1306203	Length:	379	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	98/382 - (25%)
Similarity:	186/382 - (48%)	Gaps:	34/382 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 NLLAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSG 94
            :|.|.:|::.::......|:..||.:|.|::|:.|:|.||.||::|.:....  ...:.|..|..
  Rat     9 SLFALELFHTLSESSPTGNIFFSPFSISSALAMVFLGTKGTTAAQLSKTFHF--DSVEDVHSRFQ 71

  Fly    95 SYQQALTR---DNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDF-HPPYNKRTADGINR 155
            |....:::   .:..:|||.:|..:...|...|....|:.:.:::..:|| |...:.|..  ||:
  Rat    72 SLNAEVSKRGASHTLKLANRLYGEKTYNFLPEFLTSTQKMYGADLAPVDFQHASEDARKE--INQ 134

  Fly   156 AVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMW 220
            .|..:|.|||.::|...:::..|:.|:||.:.:...|::.|....|....||.....:..|..|:
  Rat   135 WVKGQTEGKIPELLAVGVVDSMTKLVLVNAIYFKGMWEEKFMKQDTTDAPFRLNKKNTKSVKMMY 199

  Fly   221 TLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLP----NRKDGLRSLQQSLSGKNLLAEIGAMSQ 281
            ..:.|.:..::.|..||:|:|||..:.||::|||    :...||:.:::.::    |.::...::
  Rat   200 QKKKFFFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQIT----LEKLREWTK 260

  Fly   282 QK------VEVLLPKFSVTFGLGLEGPFKKLGVHTMF-SRDGDFGNM---YRMFVSHFINAVEHK 336
            ::      |.|.||:|.:.....|.....:||:..:| |...|...|   ..:|:|..:    ||
  Rat   261 RENLENIDVHVKLPRFKIEESYILNSNLGRLGLQDLFNSSKADLSGMSGSRDLFISKIV----HK 321

  Fly   337 ANVEVTEAGVDQPLETGLLKG--LFSRSKKFEADHPFVFAIKYKD--SIAFIGHIAN 389
            |.|||.|.|.:....|..:..  :....::|.|||||:|.|::..  ::.|:|.:.:
  Rat   322 AFVEVNEEGTEAAAATAGIATFCMLLPEEEFTADHPFIFFIRHNPTANVLFLGRVCS 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	98/378 (26%)
Serpinb1a	NP_001026812.1	SERPIN	4..379	CDD:294093	98/382 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.030