Protein Alignment Spn43Ab and SERPINA11

DIOPT Version :9

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 86/374 - (22%)
• Similarity: 172/374 - (45%)
• Gaps: 30/374 - (8%)

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG---PGDADAVSQ--R 92
            |..||..:||| ...|:..||.:|.:::||..:||:..|::.:.:||...   ..:|| :.|  |
Human    58 ALRLYKELAAD-APGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEAD-IHQGFR 120

  Fly    93 SGSYQQALTRDN-NFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRA 156
            |..:..||.... ..::.|::::::.|:.:..:.|..:..:.:.....:|..  :..|...||..
Human   121 SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTD--SVTTGRQINDY 183

  Fly   157 VATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKR-SFRTGSGQSVKVDTMW 220
            :..:|.|::.|.| .|...| |..|:.|.:.:.|.|:..|...:|:|: ||......|::|..|.
Human   184 LRRQTYGQVVDCL-PEFSQD-TFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMH 246

  Fly   221 TLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLAEIGAMSQQKVE 285
            ..:...:.....|...|:::.|:....::|:|....|  ::.::.:|..:.|......:....::
Human   247 QKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK--MKQVEAALQPQTLRKWGQLLLPSLLD 309

  Fly   286 VLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPL 350
            :.||:||::....||....::|:..:.:.:.||..:... ::..|:.|.|||.|:::|.|.
Human   310 LHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQ-LNKTISKVSHKAMVDMSEKGT---- 369

  Fly   351 ETGLLKGLFSRSKKFEA--------DHPFVFAI--KYKDSIAFIGHIAN 389
            |.|...||.|:......        :.||:..:  ....|:.|:|.:.|
Human   370 EAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	85/370 (23%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	85/370 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010