Protein Alignment Spn43Ab and Serpina1

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001421270.1
• Gene: Serpina1 / 24648
• RGDID: 3326
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 424
• Identity: 109/424 - (25%)
• Similarity: 187/424 - (44%)
• Gaps: 55/424 - (12%)

  Fly     1 MAVIISCLLLLLA------------------TVSQSKTVGYDAAADRNL--LAADLYNAVAADHL 45
            ||..||..|||||                  |..|.::..|...:. ||  .|..||..:.....
  Rat     1 MAPSISRGLLLLAGLCCLAPSFLAEDAQETDTSQQDQSPTYRKISS-NLADFAFSLYRELVHQSN 64

  Fly    46 NENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG----PGDADAVSQRSGSYQQALTR-DNN 105
            ..|:..||.:|.::.|:..:|:||.|..::.:||...    | :|| :.:......|.|.| |:.
  Rat    65 TSNIFFSPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQIP-EAD-IHKAFHHLLQTLNRPDSE 127

  Fly   106 FRL--ANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADG------INRAVATKTN 162
            .:|  .|.:::|:||:....|.:..:..:.|....::|        ||.      ||..|...|.
  Rat   128 LQLNTGNGLFVNKNLKLVEKFLEEVKNNYHSEAFSVNF--------ADSEEAKKVINDYVEKGTQ 184

  Fly   163 GKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNY 227
            |||.|:::.  |::.|...:||.:.:...|::.|..:.|....|......:|||..|..|..|:.
  Rat   185 GKIVDLMKQ--LDEDTVFALVNYIFFKGKWKRPFNPEHTRDADFHVDKSTTVKVPMMNRLGMFDM 247

  Fly   228 AEVNSLDAKVVELPYQNPDFSMLLLLPNRKDG-LRSLQQSLSGKNLLAEIGAMSQQKVEVL-LPK 290
            ...::|.:.|:.:.|.. :.:.:.|||:  || ::.|:|:|: |:|::......|.:..:| .||
  Rat   248 HYCSTLSSWVLMMDYLG-NATAIFLLPD--DGKMQHLEQTLT-KDLISRFLLNRQTRSAILYFPK 308

  Fly   291 FSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLL 355
            .|::....|:.....||:..:|:.|.|...:..........|| |||.:.:.|.|.:....|.:.
  Rat   309 LSISGTYNLKTLLSSLGITRVFNNDADLSGITEDAPLKLSQAV-HKAVLTLDERGTEAAGATVVE 372

  Fly   356 KGLFSRSKKFEADHPFVFAIKYKD--SIAFIGHI 387
            ....|...:.:.||||:|.|...:  |..|:|.:
  Rat   373 AVPMSLPPQVKFDHPFIFMIVESETQSPLFVGKV 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	97/380 (26%)
Serpina1	NP_001421270.1	serpinA1_A1AT	44..411	CDD:381012	97/381 (25%)
		RCL	367..386		2/18 (11%)