DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinb6d

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001070258.1	Gene:	Serpinb6d / 238568	MGIID:	2667783	Length:	375	Species:	Mus musculus

Alignment Length:	361	Identity:	94/361 - (26%)
Similarity:	168/361 - (46%)	Gaps:	21/361 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQQALTRDNN-- 105
            |..::|:.:||.:|.||:|:..:|||..||.:::|.|.|....:|........:...|...|.
Mouse    21 DDTSKNIFLSPPSIASSLAMTLLGAKENTARQIRQTLSLDKCSSDPCEDIHQDFHLLLNEVNKTD 85

  Fly   106 ----FRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKIT 166
                .:..|.:::.:....|.||:|.:|:.:.:.|::|||... .:::...||..|...|:.||.
Mouse    86 PGIILKTENRLFVEKTFHIKKSFKDASQKFYKAEIEELDFKGD-TEQSRQHINTWVTKNTDEKIK 149

  Fly   167 DILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVN 231
            |:|....:|..|..|:||...:...|:|.|..:.|.:..||........|..|:....|....:.
Mouse   150 DLLSPGSVNSNTRLVLVNDFYFKGYWEKPFNKEDTREMPFRVSKNVVKPVQMMFQKSTFKITYIE 214

  Fly   232 SLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLL--AEIGAMSQQKVEVLLPKFSVT 294
            .:..|::.|||.....:|:::||:....||.|::.::.:..:  ..:..|::::|||.||:|.:.
Mouse   215 EISTKILLLPYAGNKLNMIIMLPDEHVELRMLEKKMTYEKFVEWTSLDKMNEEEVEVFLPRFKLE 279

  Fly   295 FGLGLEGPFKKLGVHTMFSRD-GDFGNMYRMFVSH----FINAVEHKANVEVTEAGVDQPLETGL 354
            ....:.....|:|:...|... .||..     :|.    |::.|.:||.:||.|.|......|.:
Mouse   280 EIYDMNNVLYKMGMTDAFEEGRADFSG-----ISSKQGLFLSKVIYKAFIEVIEKGTKVAAATDI 339

  Fly   355 -LKGLFSRSKKFEADHPFVFAIKYKDSIAFIGHIAN 389
             :.|....:..|.|||||:|....:| ...||..::
Mouse   340 VMMGASPTTHTFCADHPFIFTHMTED-FMIIGRFSS 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	94/357 (26%)
Serpinb6d	NP_001070258.1	SERPIN	4..375	CDD:294093	94/361 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930