Protein Alignment Spn43Ab and Serpina1e

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_033273.1
• Gene: Serpina1e / 20704
• MGIID: 891967
• Length: 413
• Species: Mus musculus
• Alignment Length: 421
• Identity: 97/421 - (23%)
• Similarity: 189/421 - (44%)
• Gaps: 44/421 - (10%)

  Fly     1 MAVIISCLLLLLA------------TVSQSKT-------VGYDAAADRNLLAADLYNAVAADHLN 46
            |...||..|||||            .|.::.|       ..::.|.:....|..||..:......
Mouse     1 MTPSISWCLLLLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNT 65

  Fly    47 ENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG---PGDADAVSQRSGSYQ---QALTR-DN 104
            .|:..||.:|.::.|:..:|:||.|.:::.:||:..   ..:||.    ..|:|   |.|.| |:
Mouse    66 SNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADI----HNSFQHLLQTLNRPDS 126

  Fly   105 NFRLA--NNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKITD 167
            ..:|:  |.:::|.:|:....|.:.|:..:.:.:..::|  ..::.....||..|...|.|||.:
Mouse   127 ELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNF--AESEEAKKVINDFVEKGTQGKIVE 189

  Fly   168 ILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNS 232
            .::.  |...|..|:.|.:.:...|:|.|..:.|::..|......:|||..|......:....::
Mouse   190 AVKK--LEQDTVFVLANYILFKGKWKKPFDPENTKQAEFHVDESTTVKVPMMTLSGMLDVHHCST 252

  Fly   233 LDAKVVELPYQNPDFSMLLLLPNRKDG-LRSLQQSLSGKNLLAEIGAMSQQKV-EVLLPKFSVTF 295
            |.:.|:.:.|.. :.:.:.|||:  || ::.|:|:|: |.|:::.....:::: ::.:|:.|::.
Mouse   253 LSSWVLLMDYAG-NATAVFLLPD--DGKMQHLEQTLN-KELISKFLLNRRRRLAQIHIPRLSISG 313

  Fly   296 GLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFS 360
            ...||.....||:..:|:...|...:........::...|||.:.:.|.|.:....|.|..|..|
Mouse   314 NYNLETLMSPLGITRIFNSGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAATVLQGGFLS 378

  Fly   361 RSKKFEADHPFVFAI--KYKDSIAFIGHIAN 389
            .......:.||:|.|  ::..|..|:|.:.:
Mouse   379 MPPILHFNRPFLFIIFEEHSQSPLFVGKVVD 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	86/376 (23%)
Serpina1e	NP_033273.1	serpinA1_A1AT	44..412	CDD:381012	87/378 (23%)
		RCL	368..387		4/18 (22%)