Protein Alignment Spn43Ab and Serpina1d

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_033272.1
• Gene: Serpina1d / 20703
• MGIID: 891968
• Length: 413
• Species: Mus musculus
• Alignment Length: 422
• Identity: 96/422 - (22%)
• Similarity: 190/422 - (45%)
• Gaps: 46/422 - (10%)

  Fly     1 MAVIISCLLLLLA------------TVSQSKT-------VGYDAAADRNLLAADLYNAVAADHLN 46
            |...||..|||||            .|.::.|       ..::.|.:....|..||..:......
Mouse     1 MTPSISWSLLLLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFALRLYRELVHQSNT 65

  Fly    47 ENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG---PGDADAVSQRSGSYQ---QALTR-DN 104
            .|:..||.:|.::.|:..:|:||.|.:::.:||:..   ..:||.    ..|:|   |.|.| |:
Mouse    66 SNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADI----HKSFQHLLQTLNRPDS 126

  Fly   105 NFRLA--NNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKITD 167
            ..:|:  |.:::|.:|:....|.:.|:..:.:.:..::|  ..::.....||..|...|.|||.:
Mouse   127 ELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNF--AESEEAKKVINDFVEKGTQGKIVE 189

  Fly   168 ILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNS 232
            .::.  |:..|...:.|.:.:...|::.|..:.||:..|......:|||..|......:....:.
Mouse   190 AVKK--LDQDTVFALANYILFKGKWKQPFDPENTEEAEFHVDESTTVKVPMMTLSGMLDVHHCSM 252

  Fly   233 LDAKVVELPYQNPDFSMLLLLPNRKDG-LRSLQQSLSGKNLLAEIGAMSQQK--VEVLLPKFSVT 294
            |.:.|:.:.|.. :.:.:.|||:  || ::.|:|:|: |.|:::. .:::::  .::.:|:.|::
Mouse   253 LSSWVLLMDYAG-NTTAVFLLPD--DGKMQHLEQTLN-KELISQF-LLNRRRSDAQIHIPRLSIS 312

  Fly   295 FGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLF 359
            ....|:.....||:..:|:...|...:........::...|||.:.:.|.|.:....|.|....:
Mouse   313 GNYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAATVLQVATY 377

  Fly   360 SRSKKFEADHPFVFAI--KYKDSIAFIGHIAN 389
            |.......||||:|.|  ::..|..|:|.:.:
Mouse   378 SMPPIVRFDHPFLFIIFEEHTQSPIFVGKVVD 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	85/377 (23%)
Serpina1d	NP_033272.1	serpinA1_A1AT	44..412	CDD:381012	86/379 (23%)
		RCL	368..387		3/18 (17%)