Protein Alignment Spn43Ab and Serpina1b

DIOPT Version :9

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_033270.3
• Gene: Serpina1b / 20701
• MGIID: 891970
• Length: 413
• Species: Mus musculus
• Alignment Length: 421
• Identity: 99/421 - (23%)
• Similarity: 188/421 - (44%)
• Gaps: 44/421 - (10%)

  Fly     1 MAVIISCLLLLLA------------TVSQSKT-------VGYDAAADRNLLAADLYNAVAADHLN 46
            |...||..|||||            .|.::.|       ..::.|.:....|..||..:......
Mouse     1 MTPSISWGLLLLAGLCCMVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNT 65

  Fly    47 ENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG---PGDADAVSQRSGSYQ---QALTR-DN 104
            .|:..||.:|.::.|:..:|:||.|.:::.:||:..   ..:||.    ..|:|   |.|.| |:
Mouse    66 SNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADI----HKSFQHLLQTLNRPDS 126

  Fly   105 NFRLA--NNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKITD 167
            ..:|:  |.:::|.:|:....|.:.|:..:.:.:..::|  ..::.....||..|...|.|||.:
Mouse   127 ELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNF--AESEEAKKVINDFVEKGTQGKIVE 189

  Fly   168 ILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNS 232
            .::.  |:..|...:.|.:.:...|:|.|..:.||:..|......:|||..|......:....:.
Mouse   190 AVKE--LDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDKSTTVKVPMMMLSGMLDVHHCSI 252

  Fly   233 LDAKVVELPYQNPDFSMLLLLPNRKDG-LRSLQQSLSGKNLLAEIGAMSQQK-VEVLLPKFSVTF 295
            |.:.|:.:.|.. :.|.:.|||  :|| ::.|:|:|: |.|:::|....::: |::.:|:.|::.
Mouse   253 LSSWVLLMDYAG-NASAVFLLP--EDGKMQHLEQTLN-KELISKILLNRRRRLVQIHIPRLSISG 313

  Fly   296 GLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFS 360
            ...|:.....||:..:|:...|...:........::...|||.:.:.|.|.:....|.......|
Mouse   314 DYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAATVFEAVPMS 378

  Fly   361 RSKKFEADHPFVFAI--KYKDSIAFIGHIAN 389
            .......||||:|.|  ::..|..|:|.:.:
Mouse   379 MPPILRFDHPFLFIIFEEHTQSPIFVGKVVD 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	88/369 (24%)
Serpina1b	NP_033270.3	SERPIN	53..410	CDD:214513	87/369 (24%)
		RCL	368..387		2/18 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010