Protein Alignment Spn43Ab and Serpina1a

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 421
• Identity: 98/421 - (23%)
• Similarity: 188/421 - (44%)
• Gaps: 44/421 - (10%)

  Fly     1 MAVIISCLLLLLA------------TVSQSKT-------VGYDAAADRNLLAADLYNAVAADHLN 46
            |...||..|||||            .|.::.|       ..::.|.:....|..||..:......
Mouse    24 MTPSISWGLLLLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNT 88

  Fly    47 ENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG---PGDADAVSQRSGSYQ---QALTR-DN 104
            .|:..||.:|.::.|:..:|:||.|.:::.:||:..   ..:||.    ..|:|   |.|.| |:
Mouse    89 SNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADI----HKSFQHLLQTLNRPDS 149

  Fly   105 NFRLA--NNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRAVATKTNGKITD 167
            ..:|:  |.:::|.:|:....|.:.|:..:.:.:..::|  ..::.....||..|...|.|||.:
Mouse   150 ELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNF--AESEEAKKVINDFVEKGTQGKIAE 212

  Fly   168 ILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNS 232
            .::.  |:..|...:.|.:.:...|:|.|..:.||:..|......:|||..|......:....::
Mouse   213 AVKK--LDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVKVPMMTLSGMLHVHHCST 275

  Fly   233 LDAKVVELPYQNPDFSMLLLLPNRKDG-LRSLQQSLSGKNLLAEIGAMSQQKV-EVLLPKFSVTF 295
            |.:.|:.:.|.. :.:.:.|||:  || ::.|:|:|| |.|:::.....:::: ::..|:.|::.
Mouse   276 LSSWVLLMDYAG-NATAVFLLPD--DGKMQHLEQTLS-KELISKFLLNRRRRLAQIHFPRLSISG 336

  Fly   296 GLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFS 360
            ...|:.....||:..:|:...|...:........::...|||.:.:.|.|.:....|.|.....|
Mouse   337 EYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAVTVLQMVPMS 401

  Fly   361 RSKKFEADHPFVFAI--KYKDSIAFIGHIAN 389
            .......||||:|.|  ::..|..|:|.:.:
Mouse   402 MPPILRFDHPFLFIIFEEHTQSPIFLGKVVD 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	87/376 (23%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	88/378 (23%)