DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinf2

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	369	Identity:	92/369 - (24%)
Similarity:	166/369 - (44%)	Gaps:	39/369 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQQA 99
            ||::.||....:.|:|:||.::..:::...:||:.||...|.:.|.:..|  ..:......:.|.
Mouse    92 DLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNTG--SCLPHLLSHFYQN 154

  Fly   100 LTRDNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTAD--GINRAVATKTN 162
            | .....|||..||:.:....|..|.:.::|.|.:...||.     .|:..|  .||:.|...|.
Mouse   155 L-GPGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLT-----GKQEEDLANINQWVKEATE 213

  Fly   163 GKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTM-------- 219
            |||.|.|..  |.|.|..:::|.:.:...|:..|....|:|..|......:|.||.|
Mouse   214 GKIEDFLSE--LPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLR 276

  Fly   220 WTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKD-GLRSLQQSLSGKNLLAEIGAMSQQK 283
            |.|       :...:.:|...|::| :.|.::::|...: .:..:..:|:...|...  ::.::.
Mouse   277 WFL-------LEQPEIQVAHFPFKN-NMSFVVVMPTYFEWNVSEVLANLTWDTLYHP--SLQERP 331

  Fly   284 VEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQ 348
            .:|.|||..:...|.|.....:||:..:|......|...:..|   :::|:|::.:|::||||:.
Mouse   332 TKVWLPKLHLQQQLDLVATLSQLGLQELFQGPDLRGISEQNLV---VSSVQHQSTMELSEAGVEA 393

  Fly   349 PLETGLLKGLFSRSKKFEADHPFVFAIKYKDSIA---FIGHIAN 389
            ...|.:.....|.| .|..:.||:|.| .:|:|.   |:|.:.|
Mouse   394 AAATSVAMNRMSLS-SFTVNRPFLFFI-MEDTIGVPLFVGSVRN 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	91/365 (25%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	91/365 (25%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100