DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpina6

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_031644.1	Gene:	Serpina6 / 12401	MGIID:	88278	Length:	397	Species:	Mus musculus

Alignment Length:	421	Identity:	88/421 - (20%)
Similarity:	180/421 - (42%)	Gaps:	61/421 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IISCLLLLLAT---VSQSKTVGYDAAADRNL------LAADLYNAVAADHLNENVVISPATIQSS 59
            :.:||..|..:   .:|:.| ..|:::.|:|      .|.:||..:.|.:.::|.:|||.:|..:
Mouse     5 LYTCLFWLCTSGLWTTQAVT-DEDSSSHRDLAPTNVDFAFNLYKRLVALNSDKNTLISPVSISMA 68

  Fly    60 MALAFVGAKGQT--------------ASELQQGLRLGPGDADAVSQRSGSYQQALTRDNN----F 106
            :|:..:..:|.|              .:|:.||.:               |..:|.:.::    .
Mouse    69 LAMLSLSTRGSTQYLENLGFNMSKMSEAEIHQGFQ---------------YLNSLLQQSDTGLEM 118

  Fly   107 RLANNIYINENLEFKGSFRDVAQRQFDS---NIDKLDFHPPYNKRTADGINRAVATKTNGKITDI 168
            .:.|.:::.:||:.|.||....:..::|   .|...|:     .:..:.||..|..||.|||..:
Mouse   119 NMGNVMFLLQNLKLKDSFLADTKHYYESEALTIPSKDW-----TKAGEQINNHVKNKTQGKIEHV 178

  Fly   169 LRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSL 233
            :..  |:.....:::|.:.....|:..|..:.|.:..|......:|||..|....|.:|...:::
Mouse   179 VSD--LDSSATLILINYIFLKGIWKLPFSPENTREEDFYVNETSTVKVPMMVQSGNISYFRDSAI 241

  Fly   234 DAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLAEIG-AMSQQKVEVLLPKFSVTFGL 297
            ..::|::.|.. :.:..::||::  |......:...::.:...| .|..:::.:.:||||::...
Mouse   242 PCQMVQMNYVG-NGTTFIILPDQ--GQMDTVVAALNRDTIDRWGKLMIPRQMNLYIPKFSMSDTY 303

  Fly   298 GLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSRS 362
            .|:.....:|:..:|:...||.:..:  .:.....|.|||.:::.|..|......|....|.|.|
Mouse   304 DLQDVLADVGIKDLFTNQSDFADTTK--DTPLTLTVLHKAMLQLDEGNVLPAATNGPPVHLPSES 366

  Fly   363 KKFEADHPFVFAI--KYKDSIAFIGHIANYA 391
            ...:.:.||:|..  ||..|...:..:.|.|
Mouse   367 FTLKYNRPFIFLAFDKYTWSSLMMSQVMNPA 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	79/386 (20%)
Serpina6	NP_031644.1	SERPIN	43..396	CDD:214513	77/379 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110