DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and Serpinb5

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_476449.2	Gene:	Serpinb5 / 116589	RGDID:	69342	Length:	375	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	102/376 - (27%)
Similarity:	183/376 - (48%)	Gaps:	32/376 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQ 97
            |.:|:..:.......|::.||..:.:|::||.|||||.||:|:.|.|..     :.|......:
  Rat    12 AVELFKQLCEKEPAGNILFSPICLSTSLSLAQVGAKGDTANEIGQVLHF-----ENVKDVPFGF- 70

  Fly    98 QALTRDNN-------FRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINR 155
            |.:|.|.|       .:|...:||:::|.....|....:|.:.:.::.:||.... :.|...||.
  Rat    71 QTITSDVNKLSSFYSLKLIKRLYIDKSLNLSTEFISSTKRPYANELETVDFKDKL-EETKGQINS 134

  Fly   156 AVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMW 220
            ::...|:|...|||....::|:|:.::||...:...|.|.|...:|::..||.....:..|..|.
  Rat   135 SIKELTDGHFEDILPENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRINKTDTKPVQMMN 199

  Fly   221 TLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLP----NRKDGLRSLQQSLSGKNLL--AEIGAM 279
            ....|....::.::.|::|||:||...|||::||    :...||..:::.|:.:.||  .....|
  Rat   200 LEATFCLGNIDDINCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEKQLNPETLLQWTNPSTM 264

  Fly   280 SQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRD-GDFGNMYR---MFVSHFINAVEHKANVE 340
            :..||::.||||.|...:..:...:.||:.::|:.. .||..|..   :.||:.|    |:..:|
  Rat   265 ANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETKGVSVSNVI----HRVCLE 325

  Fly   341 VTEAGVDQPLETGLLKGLFSRSKKFEADHPFVFAIKYKD--SIAFIGHIAN 389
            :||.|.|.....|  ..:.....:|:|||||:|.:::..  :|.|:|..::
  Rat   326 ITEDGGDSIEVPG--SRILQHKDEFKADHPFLFIVRHNKTRNIVFLGKFSS 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	102/372 (27%)
Serpinb5	NP_476449.2	serpinB5_maspin	1..375	CDD:381013	102/376 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930