Protein Alignment Spn43Ab and Serpina3a

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: XP_006240581.2
• Gene: Serpina3a / 100909605
• RGDID: 6502633
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 373
• Identity: 92/373 - (24%)
• Similarity: 169/373 - (45%)
• Gaps: 36/373 - (9%)

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGSYQ 97
            |..||..:...:.::|:|.|..:|.:::.|..:|||..|..|:.:||:....:........| |:
  Rat    45 AFSLYKELVLKNPDKNIVFSSFSISTALVLLSLGAKNNTLKEILEGLKFNLTETPEAEIHQG-YE 108

  Fly    98 QALTRDN------NFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTADGINRA 156
            ..|.|.|      .....:.::|.::|:....|::.|:..:.:.....||..|:..:..  ||..
  Rat   109 HLLQRLNLPGDQVQISTGSALFIKKHLQILAEFQEKARALYQAEAFSTDFQQPHEAKKL--INDY 171

  Fly   157 VATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWT 221
            |..:|.|||.:::  .:|:.:|..|:||.:.:...|:..|....|.:..|.....:|||| .|..
  Rat   172 VRKQTQGKIKELI--SVLDKKTSMVLVNYIYFKGKWKMPFDPHDTFQSEFYLDEKKSVKV-PMMK 233

  Fly   222 LQNFN--YAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLAEIGAMSQQKV 284
            ::...  |.....|...|:||.|.. :.|.|.:||: :..::.::.||..:.|......:..:::
  Rat   234 IEKLTTPYFRDEELSCSVLELKYTG-NASALFILPD-QGRMQQVEASLQPETLRRWKDTLRPRRI 296

  Fly   285 -EVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNM---YRMFVSHFINAVEHKANVEVTEAG 345
             |:.:||||::..:.|.....:||:..:||:..|...:   ..:.||.    |.|||.::|||.|
  Rat   297 DELRMPKFSISTDMRLGDILPELGIREVFSQQADLSRITGAKDLSVSQ----VVHKAVLDVTETG 357

  Fly   346 VDQPLETGLLKGLFSRSKKF-----EADHPFVFAIKYKDSIAFIGHIA 388
            .:....||:  .:.....||     ..:.||:..|...::     |||
  Rat   358 TEAAAATGV--KIIPMCAKFYYVTMYFNRPFLMIISDTNT-----HIA 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	92/373 (25%)
Serpina3a	XP_006240581.2	serpinA3_A1AC	27..408	CDD:381019	92/373 (25%)