| Sequence 1: | NP_651839.1 | Gene: | Sox100B / 45039 | FlyBaseID: | FBgn0024288 | Length: | 529 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_008872.1 | Gene: | SOX10 / 6663 | HGNCID: | 11190 | Length: | 466 | Species: | Homo sapiens |
| Alignment Length: | 487 | Identity: | 146/487 - (29%) |
|---|---|---|---|
| Similarity: | 194/487 - (39%) | Gaps: | 114/487 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 33 KAQGQGGRKEDER----ITTAVMKVLEGYDWNLVQASAKA-PTDRKKEHIKRPMNAFMVWAQAAR 92
Fly 93 RVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLP 157
Fly 158 SQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDV 222
Fly 223 FSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSL 287
Fly 288 LLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGG 352
Fly 353 YTGSRVSYPAYSY------PANGGHFATEEQQQQQAL--------QASEALNYKPAAADIDPKEI 403
Fly 404 DQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAA 468
Fly 469 SSA------SQNPNF-GPQQPYANGAASMTPT 493 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sox100B | NP_651839.1 | SOX-TCF_HMG-box | 76..146 | CDD:238684 | 50/69 (72%) |
| SOX10 | NP_008872.1 | Sox_N | 12..93 | CDD:315171 | 15/37 (41%) |
| Dimerization (DIM). /evidence=ECO:0000303|PubMed:31194875 | 62..102 | 12/39 (31%) | |||
| SOX-TCF_HMG-box | 103..173 | CDD:238684 | 50/69 (72%) | ||
| Nuclear export signal | 134..145 | 8/10 (80%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 160..199 | 21/41 (51%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 212..274 | 18/128 (14%) | |||
| Transactivation domain (TAM). /evidence=ECO:0000303|PubMed:31194875 | 228..310 | 25/143 (17%) | |||
| Transactivation domain (TAC). /evidence=ECO:0000303|PubMed:31194875 | 353..466 | 27/115 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 354..375 | 4/20 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 433..466 | 6/21 (29%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..67 | 4/11 (36%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 115 | 1.000 | Domainoid score | I6018 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0527 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 181 | 1.000 | Inparanoid score | I3995 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000028 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40903 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR45803 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5318 |
| SonicParanoid | 1 | 1.000 | - | - | X1210 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.990 | |||||