Protein Alignment Sox100B and sox9a

DIOPT Version :9

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_571718.1
• Gene: sox9a / 60641
• ZFINID: ZDB-GENE-001103-1
• Length: 462
• Species: Danio rerio
• Alignment Length: 570
• Identity: 163/570 - (28%)
• Similarity: 225/570 - (39%)
• Gaps: 193/570 - (33%)

  Fly     1 MSDSSSSNCSKDRA---------------KPVETLVLANYALKAEQKKAQGQ-GGRKEDER---- 45
            :||:.|.:.|:|.|               :|.|..:||          |.|. |..|:||.
Zfish    18 LSDAPSPSMSEDSAGSPCPSASGSDTENTRPAENSLLA----------ADGTLGDFKKDEEDKFP 72

  Fly    46 --ITTAVMKVLEGYDWNLVQASAKA-PTDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSEL 107
              |..||.:||:||||.||....:. .:.:.|.|:||||||||||||||||.::.|||||.|:||
Zfish    73 VCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAEL 137

  Fly   108 SKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMT 172
            ||:|||||:.|.:.:|:||:|.||:||:.||::||||||||||:|
Zfish   138 SKTLGKLWRLLNEVEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK-------------------- 182

  Fly   173 LSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACA 237
                         |..|||                   |.:..||..:.:..| |..|:|..|
Zfish   183 -------------SVKNGQ-------------------SESEDGSEQTHISPN-AIFKALQQA-- 212

  Fly   238 ASLMEQSLIETGLDSPCSTASSMSSL--------------TPPATP-YNVAPSNAKASAANNPSL 287
                         |||   ||||..:              |||.|| .:..|..|.......|
Zfish   213 -------------DSP---ASSMGEVHSPSEHSGQSQGPPTPPTTPKTDTQPGKADLKREARP-- 259

  Fly   288 LLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLE--NINGY 350
            |......|::                     :|:|....|..|.          |.:|  ::|.:
Zfish   260 LQENTGRPLS---------------------INFQDVDIGELSS----------DVIETFDVNEF 293

  Fly   351 GGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMT 415
            ..|........|   |..||:.|...:.|..:.|:|:.....||..| .|: ......:|:.|
Zfish   294 DQYLPPNGHQNA---PYAGGYAAWMTKPQNGSPQSSQLTPLNPAEPD-QPR-TTHIKTEQLSP-- 351

  Fly   416 QHHHPHHTHPLH---------HPLHHSPPLNSSASLSSA--CSSASSQQPVAEYYEHLG------ 463
            .|::.....|.|         |..|:|   .|..|::.|  ..|.|.|...:.||.|.|
Zfish   352 SHYNEQQGSPQHISYGSFNVQHLQHYS---TSFPSITRAQYDYSDSHQGGASSYYTHAGGQSSGL 413

  Fly   464 YSP-AASSASQNPNFGPQQPYANGAASMTPTLGDPA-PQQELQSQQQEQQ 511
            ||. :..|:||.|.:.|          :..:.|.|: ||.....|..:||
Zfish   414 YSTFSYMSSSQRPMYTP----------IADSTGVPSIPQSNHSPQHWDQQ 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	47/69 (68%)
sox9a	NP_571718.1	Sox_N	22..96	CDD:289229	25/83 (30%)
		SOX-TCF_HMG-box	106..176	CDD:238684	47/69 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6177
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I3937
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm24602
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45803
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1210
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.960