Protein Alignment Sox100B and Sox21b

DIOPT Version :10

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: XP_061509694.1
• Gene: Sox21b / 4577582
• VectorBaseID: AGAMI1_014325
• Length: 529
• Species: Anopheles gambiae
• Alignment Length: 556
• Identity: 132/556 - (23%)
• Similarity: 199/556 - (35%)
• Gaps: 201/556 - (36%)

  Fly     1 MSDSSSSNCSKDRAKPVETLVLANYALKAEQKKAQGQGGRKEDERITTAVMKVLEGYDWN--LVQ 63
            :|..:|.:.|...:..:.:|.|.:..|.|....|.   ...:...:...|..:|.|...|  |.|
Mosquito    70 LSIPTSQSLSNQSSHALNSLGLHSQNLHASSVNAL---HNSQTTNLHQNVSGLLNGAAGNGLLGQ 131

  Fly    64 ASAKAPTDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFME 128
            |..|.|.:   |||||||||||||::..||.:::..|.:.|||:||.||..||.|.:.:|:||::
Mosquito   132 AMLKKPAE---EHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEDEKRPFID 193

  Fly   129 FAEKLRMTHKQEHPDYKYQPRRK-----------------------KARVLPSQQSGEGGSPGPE 170
            .|::||..|.:|||||||:||||                       :|.:.||.     .:||..
Mosquito   194 EAKRLRAMHMKEHPDYKYRPRRKPKPIRRDGYPYPMTYPSVPVDALRAGITPSY-----FAPGAP 253

  Fly   171 MTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKS--LN 233
            ..|.:.:..:..|.:.:|.                           |:..|| |..|..:|  ||
Mosquito   254 YHLGSHLSQASPPTTQSSI---------------------------SSQMDV-SKFALDRSAYLN 290

  Fly   234 SACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVAN 298
            :|.|.:|.:.:..:|   :|.|.....:|:...|. ::......:|.||.|.:..:.::
Mosquito   291 TAAAGALYDTAKSQT---NPYSAYLDPTSVLTKAY-FDSKMYQDRAQAAANYAFDISKI------ 345

  Fly   299 AGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAY 363
                ||...:            .|.|..|..|....|.:.|:....::
Mosquito   346 ----YGTTAQ------------QQQQQLGSSSSTSSGSSSQQQQQQQH----------------- 377

  Fly   364 SYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHH 428
                       ::|||||..|..:                 |:...|:     ...|||   |||
Mosquito   378 -----------QQQQQQQQHQQHQ-----------------QHQQHQL-----QQSPHH---LHH 406

  Fly   429 PLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASSASQNPNFGPQQPYANGAAS---- 489
            ||||                                               |....|||||
Mosquito   407 PLHH-----------------------------------------------QHQLQNGAASGGLD 424

  Fly   490 ---MTPTLGDPAPQQELQSQQQEQQHQNPSQHHLWG 522
               .||.|||..|  :::.|..|....:|...|.:|
Mosquito   425 ERESTPQLGDVTP--DIKPQIVEPLEGSPLHSHSYG 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	HMG-box_SoxE	76..150	CDD:438840	40/73 (55%)
Sox21b	XP_061509694.1	None