DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox100B and MEIOSIN

DIOPT Version :9

Sequence 1:	NP_651839.1	Gene:	Sox100B / 45039	FlyBaseID:	FBgn0024288	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_011525873.1	Gene:	MEIOSIN / 388553	HGNCID:	44318	Length:	644	Species:	Homo sapiens

Alignment Length:	202	Identity:	44/202 - (21%)
Similarity:	76/202 - (37%)	Gaps:	70/202 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDSSSSNCSKD-------------RAKPVET--------------LVLANYALKAEQKKAQGQGG 39
            |.||||:.|:|             :|.||.|              ..||:..|.||:|..:||
Human   463 SSSSSSSSSEDSDSEPLWKQREDMQANPVGTPGSSEEDEDTTWTPTRLASPLLAAEKKATKGQ-- 525

  Fly    40 RKEDERITTAVMKVLEGYDWNLVQASAKAPTDRKK-----EHIKRPMNAFMVWAQAARRVMSKQY 99
                                 :.:|..| |.::||     :..|:.:|.|:::.:..|:...:..
Human   526 ---------------------VARAPVK-PKEKKKGPCPPQMKKKCVNGFIMFCRMNRKQYIRSC 568

  Fly   100 PHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQ--------------EHPDYKYQPRR 150
            |...::..:|.|.:||:.:...:::|:...|.:....|.:              |.|...||...
Human   569 PGTASTAATKELAQLWRVMTQQERRPYCTKARRFSRQHNRIVKQDGSSSEAEDWETPKPFYQLLA 633

  Fly   151 KKARVLP 157
            :||..||
Human   634 EKALPLP 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	14/83 (17%)
MEIOSIN	XP_011525873.1	HMG-box	547..606	CDD:294061	11/58 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900