Protein Alignment Sox100B and sox17

DIOPT Version :10

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_571362.2
• Gene: sox17 / 30544
• ZFINID: ZDB-GENE-991213-1
• Length: 413
• Species: Danio rerio
• Alignment Length: 456
• Identity: 119/456 - (26%)
• Similarity: 173/456 - (37%)
• Gaps: 145/456 - (31%)

  Fly    63 QASAKAPTDRKKE-HIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPF 126
            :.||..|...|.| .|:||||||||||:..|:.:::|.|.|.|:||||.|||.||.|...||:||
Zfish    48 KCSAAGPGRGKSEPRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALPMVDKRPF 112

  Fly   127 MEFAEKLRMTHKQEHPDYKYQPRRKK-----ARVLPSQQSGEGGSPG---PEMTL-----SATMG 178
            :|.||:||:.|.|:||:|||:|||:|     .|:.||..     .||   .:|||     ||...
Zfish   113 VEEAERLRVKHMQDHPNYKYRPRRRKQVKRNKRLEPSFP-----LPGMCDAKMTLCTEGMSAGYS 172

  Fly   179 SSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQ 243
            .:|.|:...::               :...:.|......:..|..:.|.|         |.|.:|
Zfish   173 GAGLPQYCENH---------------TLFESYSLPTPDPSPMDAGTTEFF---------AQLQDQ 213

  Fly   244 SLI------------ETGL--DSPC----STASSMSSLTPPATPYNVAPSNAKASAANNPSLLLR 290
            |..            :|.:  |:.|    .|..|..|       :::|.||...:..:|
Zfish   214 SAFSYHHQQEHHFQEQTNILNDTHCHGNTQTLKSRQS-------HSIAYSNINTNTNSN------ 265

  Fly   291 QLSEPVANAGDGYGVLLEAGREYVAIGEVNYQ---GQSAGVQSGAEGGGAGQEMDFLENINGYGG 352
             |..|: ||               .:..:|.|   .::|..|.....|      ..|...|....
Zfish   266 -LHAPI-NA---------------QLSSINLQQVFHENANPQISHHPG------THLNIFNRSPS 307

  Fly   353 YTGSRVSYPAY--------------SYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEI 403
            .:......|||              |......|..:....:||::  :||.:....|.....:.:
Zfish   308 SSSHHAMTPAYLNCPSTLDTFYNSSSQMKELSHCVSSHTHKQQSI--AEAQSQASTATHSSGQMV 370

  Fly   404 DQYFMDQML----PMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGY 464
            |:...:..|    |                   |.||..|..:|:..|.|||    |.||  .||
Zfish   371 DEVEFEHCLSFGVP-------------------SAPLPGSDLISTVLSDASS----AVYY--CGY 410

  Fly   465 S 465
            :
Zfish   411 N 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	HMG-box_SoxE	76..150	CDD:438840	43/73 (59%)
sox17	NP_571362.2	HMG-box_SoxF_SOX17	57..137	CDD:438850	46/79 (58%)
		Sox17_18_mid	<186..225	CDD:463454	8/47 (17%)