Protein Alignment Sox100B and Sox8

DIOPT Version :9

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001100459.1
• Gene: Sox8 / 302993
• RGDID: 1309072
• Length: 463
• Species: Rattus norvegicus
• Alignment Length: 522
• Identity: 149/522 - (28%)
• Similarity: 205/522 - (39%)
• Gaps: 188/522 - (36%)

  Fly    36 GQGGRKE-----DER----ITTAVMKVLEGYDWNLVQASAK---APTDRKKEHIKRPMNAFMVWA 88
            |.|||.:     |||    |..||.:||:||||:||....:   ..|.:.|.|:|||||||||||
  Rat    46 GGGGRGDTAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWA 110

  Fly    89 QAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKA 153
            |||||.::.|||||.|:||||:|||||:.|.:|:|:||:|.||:||:.||::||||||||||:|:
  Rat   111 QAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS 175

  Fly   154 RVLPSQQSGEGGSP------GPEMTLSATMGSS-----------GKP-----------RSSNSNG 190
             |...:...:.|:.      ||.......:|.:           |.|           ::||.:.
  Rat   176 -VKTGRSDSDSGTELGHHPGGPMYKTDTVLGDAHRHSDHTGQTHGPPTPPTTPKTDLHQASNGSK 239

  Fly   191 QRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCS 255
            |....:|....|.|......|:.::...||:|.||   |.:.:    ....:|.|
  Rat   240 QELRLEGRRLVDSGRQNIDFSNVDISELSSEVISN---MDTFD----VHEFDQYL---------- 287

  Fly   256 TASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVN 320
                              |.|..::.|..||         .|.|...||     |..|
  Rat   288 ------------------PLNGHSALATEPS---------QATASGSYG-----GASY------- 313

  Fly   321 YQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQA 385
                   ..|||.|.||.                      |.:::..
  Rat   314 -------SHSGATGIGAS----------------------PVWAHKG------------------ 331

  Fly   386 SEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHH--PLHHSP------------PL 436
                   ..:|...|.|..        |:..|.......|.|:  ..|.||            .:
  Rat   332 -------APSASASPTEAG--------PLRPHIKTEQLSPSHYNDQSHGSPGRADYGSYSAQASV 381

  Fly   437 NSSASLSSACSSASSQ-----QPVAEYYE-HLGYSPAASSASQNPNF-GPQQPYA----NGAASM 490
            .::||.::|.|.||:|     ...:.||. :.||.|   |..|.|.| ..::|||    || .||
  Rat   382 TTAASATAASSFASAQCDYTDLQASNYYSPYPGYPP---SLYQYPYFHSSRRPYASSLLNG-LSM 442

  Fly   491 TP 492
            .|
  Rat   443 PP 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	48/69 (70%)
Sox8	NP_001100459.1	Sox_N	18..86	CDD:403592	18/39 (46%)
		SOX-TCF_HMG-box	98..168	CDD:238684	48/69 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I5872
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm45041
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45803
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1210
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.910