Protein Alignment Sox100B and Sox1

DIOPT Version :10

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_033259.2
• Gene: Sox1 / 20664
• MGIID: 98357
• Length: 391
• Species: Mus musculus
• Alignment Length: 506
• Identity: 115/506 - (22%)
• Similarity: 168/506 - (33%)
• Gaps: 230/506 - (45%)

  Fly    70 TDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLR 134
            |...::.:||||||||||::..||.|:::.|.:.|||:||.||..||.:.:::|:||::.|::||
Mouse    44 TKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLR 108

  Fly   135 MTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNA 199
            ..|.:|||||||:||||...:|...          :.:|:..:.::|            ||.|.|
Mouse   109 ALHMKEHPDYKYRPRRKTKTLLKKD----------KYSLAGGLLAAG------------AGGGGA 151

  Fly   200 AADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLT 264
            |..:|
Mouse   152 AVAMG------------------------------------------------------------ 156

  Fly   265 PPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQ 329
                                              .|.|.|.        .|:|:   :.:|.|
Mouse   157 ----------------------------------VGVGVGA--------AAVGQ---RLESPG-- 174

  Fly   330 SGAEGGGAGQEMDFLENINGY--GGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYK 392
             ||.|||       ..::||:  |.|.||..:..|          |....|:.|.     |....
Mouse   175 -GAAGGG-------YAHVNGWANGAYPGSVAAAAA----------AAAMMQEAQL-----AYGQH 216

  Fly   393 PAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHP-----------------LHHSPPLNSSA 440
            |.|....|                |.||.|.|| |||                 |.:||..||..
Mouse   217 PGAGGAHP----------------HAHPAHPHP-HHPHAHPHNPQPMHRYDMGALQYSPISNSQG 264

  Fly   441 SLSS-----------ACSSASSQQPVAEYYEHLGYSPAASSAS------------QNPNFGPQQP 482
            .:|:           |.::|::....|.....:..:.||::||            ..|:..|..|
Mouse   265 YMSASPSGYGGIPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAP 329

  Fly   483 YANGAASMTPTLGD---------PA-----PQQELQSQQQEQQHQNPSQHH 519
                |.|..|..||         ||     |.....:..|.:.|..| ||:
Mouse   330 ----AHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLP-QHY 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	HMG-box_SoxE	76..150	CDD:438840	38/73 (52%)
Sox1	NP_033259.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		1/7 (14%)
		HMG-box_SoxB	49..128	CDD:438790	41/78 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		12/51 (24%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	342..350		0/7 (0%)