Protein Alignment Sox100B and sem-2

DIOPT Version :10

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 106/478 - (22%)
• Similarity: 156/478 - (32%)
• Gaps: 194/478 - (40%)

  Fly    38 GGRKEDERITTAVMKVLEGYDWNLVQASAKAPTDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHL 102
            ||.|..::   |:.|.:..|       |......:...||||||||||||:|..||.:.:..|.:
 Worm    64 GGYKHAQQ---AIPKSVTPY-------SDATNCKKSSNHIKRPMNAFMVWSQMERRKICEHQPDM 118

  Fly   103 QNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSP 167
            .|:|:||.||..|::|.|.:|.||:..||:||:.|.||:|||||:||:|..:
 Worm   119 HNAEISKQLGSRWRSLTDEEKAPFVAEAERLRVCHMQEYPDYKYKPRKKPKK------------- 170

  Fly   168 GPEMTL------SATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNS-SDVFSN 225
            .|:.||      .|.......||.::...::|                 ...|....| :..|.|
 Worm   171 NPDGTLQQPAQPQAPQQQQAPPRGASPQARQR-----------------KRPNTDQQSETQQFQN 218

  Fly   226 EAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLR 290
               .||:.       :||..:                            .||..|.|
 Worm   219 ---FKSVK-------VEQDWM----------------------------GNAHMSHA-------- 237

  Fly   291 QLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTG 355
                                                            |:|.|
 Worm   238 ------------------------------------------------QKMPF------------ 242

  Fly   356 SRVSYPAYSYPANGGH-------------FATEEQQQQQALQASEALNYKPAAADIDPKEIDQYF 407
                :|:|..|:..||             |..:..||..|.|     ::..|.:   |..:....
 Worm   243 ----HPSYPSPSEFGHAPLTPESGFYDDYFTQQHHQQHFASQ-----HHNSAGS---PLRMTNLG 295

  Fly   408 MDQMLPMTQHHHPHHTHPLHHP--LHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASS 470
            ||..:|.....|.......:||  ||.|||......:.|..|.:|            ||:..::|
 Worm   296 MDMGMPPQMMGHNSGFGAGNHPFYLHTSPPSVDQDDMRSLSSGSS------------GYADCSAS 348

  Fly   471 --ASQNPNFGPQQPYANGAASMT 491
              ::.:||.......|..|.:.|
 Worm   349 EQSTSSPNSAGVVTMATAATTTT 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	HMG-box_SoxE	76..150	CDD:438840	41/73 (56%)
sem-2	NP_740846.1	HMG-box_SoxC	92..159	CDD:438838	35/66 (53%)