Protein Alignment Sox100B and sox10

DIOPT Version :9

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_571950.1
• Gene: sox10 / 140616
• ZFINID: ZDB-GENE-011207-1
• Length: 485
• Species: Danio rerio
• Alignment Length: 505
• Identity: 145/505 - (28%)
• Similarity: 206/505 - (40%)
• Gaps: 143/505 - (28%)

  Fly    23 ANYALKAEQKKAQGQG-------------GRKEDER----ITTAVMKVLEGYDWNLVQASAKAPT 70
            |:..|..:|.:..|.|             ..:||:|    |..||.:||.||||.||....:..:
Zfish    36 ADSPLPGQQSQMSGIGDDGAGVSGGVSVKSDEEDDRFPIGIREAVSQVLNGYDWTLVPMPVRVNS 100

  Fly    71 DRK-KEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLR 134
            ..| |.|:||||||||||||||||.::.|||||.|:||||:|||||:.|.::||:||:|.||:||
Zfish   101 GSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNETDKRPFIEEAERLR 165

  Fly   135 MTHKQEHPDYKYQPRRKK---------------ARVLPSQ-----------QSGEGGSP------ 167
            ..||:::|:|||||||:|               ..|..||           ..|..|||
Zfish   166 KQHKKDYPEYKYQPRRRKNGKPGSSSEADAHSEGEVSHSQSHYKSLHLEVAHGGAAGSPLGDGHH 230

  Fly   168 ---------------GPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTIS------ 211
                           .|:..|.......||    ...|..|:|.| ..||..|.:|:.|
Zfish   231 PHATGQSHSPPTPPTTPKTELQGGKSGEGK----REGGASRSGLG-VGADGSSASSSASGKPHID 290

  Fly   212 --HANVGSNSSDVFSN-EAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVA 273
              :.::|..|.||.:| |.|  .:|.      .:|.|...|.....:|||:.|:  .|:..|.::
Zfish   291 FGNVDIGEISHDVMANMEPF--DVNE------FDQYLPPNGHPQASATASAGSA--APSYTYGIS 345

  Fly   274 PSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAG 338
            .:.|.||..:...|..:||........||       |:..:. .|.::.|.:|.
Zfish   346 SALAAASGHSTAWLSKQQLPSQQHLGADG-------GKTQIK-SETHFPGDTAA----------- 391

  Fly   339 QEMDFLENINGYGGYTGSRVSY-----PAYS--YPANGGHFATEEQQQQQA-----LQASEALNY 391
                           :||.|:|     |.||  :|:........|..:.||     ..:|:....
Zfish   392 ---------------SGSHVTYTPLTLPHYSSAFPSLASRAQFAEYAEHQASGSYYAHSSQTSGL 441

  Fly   392 KPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSAS 441
            ..|.:.:.|.:...|        |....|......|.|.|...|:.::.|
Zfish   442 YSAFSYMGPSQRPLY--------TAIPDPGSVPQSHSPTHWEQPVYTTLS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	46/69 (67%)
sox10	NP_571950.1	Sox_N	13..97	CDD:289229	19/60 (32%)
		SOX-TCF_HMG-box	107..177	CDD:238684	46/69 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6177
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I3937
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm24602
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45803
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5318
SonicParanoid	1	1.000	-	-		X1210
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.990