Protein Alignment Sox100B and SOX21

DIOPT Version :10

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_009015.1
• Gene: SOX21 / 11166
• HGNCID: 11197
• Length: 276
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 94/317 - (29%)
• Similarity: 129/317 - (40%)
• Gaps: 106/317 - (33%)

  Fly    75 EHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQ 139
            :|:||||||||||::|.||.|:::.|.:.|||:||.||..||.|.:|:|:||::.|::||..|.:
Human     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70

  Fly   140 EHPDYKYQPRRKKARVL---------------------PSQQSGEGGSPGPEMTLSATMGSSGKP 183
            |||||||:||||...:|                     |:.::|.|        |.|..|....|
Human    71 EHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAG--------LHAGAGGGLVP 127

  Fly   184 RSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIET 248
            .|..:|.::.|....|||           |.|      .|...|...:..:|.||:....||::.
Human   128 ESLLANPEKAAAAAAAAA-----------ARV------FFPQSAAAAAAAAAAAAAGSPYSLLDL 175

  Fly   249 GLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREY 313
            |  |..:..||.||..|.|:                      .|..|.|.||..:|
Human   176 G--SKMAEISSSSSGLPYAS----------------------SLGYPTAGAGAFHG--------- 207

  Fly   314 VAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVS--YPAYSYPAN 368
                        |...:.|....|             ||:|.|..|  .|.|..|.|
Human   208 ------------AAAAAAAAAAAA-------------GGHTHSHPSPGNPGYMIPCN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	HMG-box_SoxE	76..150	CDD:438840	42/73 (58%)
SOX21	NP_009015.1	HMG-box_SoxB	6..85	CDD:438790	45/78 (58%)
		SOXp	77..>95	CDD:463537	6/17 (35%)