DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox100B and SOX21

DIOPT Version :9

Sequence 1:NP_651839.1 Gene:Sox100B / 45039 FlyBaseID:FBgn0024288 Length:529 Species:Drosophila melanogaster
Sequence 2:NP_009015.1 Gene:SOX21 / 11166 HGNCID:11197 Length:276 Species:Homo sapiens


Alignment Length:317 Identity:94/317 - (29%)
Similarity:129/317 - (40%) Gaps:106/317 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 EHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQ 139
            :|:||||||||||::|.||.|:::.|.:.|||:||.||..||.|.:|:|:||::.|::||..|.:
Human     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70

  Fly   140 EHPDYKYQPRRKKARVL---------------------PSQQSGEGGSPGPEMTLSATMGSSGKP 183
            |||||||:||||...:|                     |:.::|.|        |.|..|....|
Human    71 EHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAG--------LHAGAGGGLVP 127

  Fly   184 RSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIET 248
            .|..:|.::.|....|||           |.|      .|...|...:..:|.||:....||::.
Human   128 ESLLANPEKAAAAAAAAA-----------ARV------FFPQSAAAAAAAAAAAAAGSPYSLLDL 175

  Fly   249 GLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREY 313
            |  |..:..||.||..|.|:                      .|..|.|.||..:|         
Human   176 G--SKMAEISSSSSGLPYAS----------------------SLGYPTAGAGAFHG--------- 207

  Fly   314 VAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVS--YPAYSYPAN 368
                        |...:.|....|             ||:|.|..|  .|.|..|.|
Human   208 ------------AAAAAAAAAAAA-------------GGHTHSHPSPGNPGYMIPCN 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox100BNP_651839.1 SOX-TCF_HMG-box 76..146 CDD:238684 39/69 (57%)
SOX21NP_009015.1 SOX-TCF_HMG-box 7..78 CDD:238684 40/70 (57%)
SOXp 77..>95 CDD:403523 6/17 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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