Protein Alignment Sox100B and sox8a

DIOPT Version :9

• Sequence 1: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001271361.1
• Gene: sox8a / 102216265
• ZFINID: ZDB-GENE-130530-719
• Length: 401
• Species: Danio rerio
• Alignment Length: 539
• Identity: 142/539 - (26%)
• Similarity: 199/539 - (36%)
• Gaps: 219/539 - (40%)

  Fly     2 SDSSSSNCSKD-----RAKPVETLVLANYALKAEQKKAQGQGGRKEDERITTAVMKVLEGYDWNL 61
            |||.||....|     .|.|.:|                 .|..:....|..||.:||:||||:|
Zfish    22 SDSPSSPSVSDDPGSRAAPPPDT-----------------DGDARFPVCIRDAVSQVLKGYDWSL 69

  Fly    62 VQASAKAPTDRK-KEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKP 125
            |....:.....| |.|:||||||||||||||||.::.|||||.|:||||:|||||:.|.:|:|:|
Zfish    70 VPMPMQGSRSLKDKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRP 134

  Fly   126 FMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNG 190
            |:|.||:||:.||:::|||||||||:|: :.|.|...|.|:   |..|..|
Zfish   135 FVEEAERLRLQHKKDYPDYKYQPRRRKS-LKPGQNEAEAGA---EKNLHHT-------------- 181

  Fly   191 QRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCS 255
                                         ..::..||.|::::        .|::.......|
Zfish   182 -----------------------------DPIYKTEAGMRAMH--------HQTIHGVQPHGP-- 207

  Fly   256 TASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVN 320
                   .|||.||    .|:...|        :::|||
Zfish   208 -------PTPPTTP----KSDQHQS--------MKRLSE-------------------------- 227

  Fly   321 YQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQA 385
                           .|.|.:||            |.|.....|....|
Zfish   228 ---------------NARQNIDF------------SNVDISELSSDVIG---------------- 249

  Fly   386 SEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHP---HHTHP------LHHPLHHSPPLNSSAS 441
                    :.:..|.:|.|||     ||:..|...   .|:.|      .||  |......:..|
Zfish   250 --------SISQFDVREFDQY-----LPLNGHTESGGGQHSSPGCFSTSFHH--HSGASAWNKPS 299

  Fly   442 LSSACSSASSQQPVAEYYE----HLGYSPAASSASQ---------NPNFGP---------QQPYA 484
            .|.:.|||:.|:|:.:..:    |.|.|..:.:.|:         :|.|..         |.||.
Zfish   300 GSPSTSSANQQRPLIKTEQLSPSHYGQSHGSPTQSELSDCADMQNSPYFTTFSGYPAGIYQYPYF 364

  Fly   485 NGA--ASMTP---TLGDPA 498
            :..  :.|||   ||..|:
Zfish   365 HSTRRSYMTPVLNTLSSPS 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	47/69 (68%)
sox8a	NP_001271361.1	Sox_N	<40..73	CDD:372113	14/49 (29%)
		SOX-TCF_HMG-box	85..155	CDD:238684	47/69 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6177
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I3937
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm24602
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45803
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1210
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.060