DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp4-19C and PPT1

DIOPT Version :9

Sequence 1:	NP_001285489.1	Gene:	Pp4-19C / 45031	FlyBaseID:	FBgn0023177	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	282	Identity:	110/282 - (39%)
Similarity:	155/282 - (54%)	Gaps:	21/282 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDV-PEKNYLFMGDFVDRGYYSVETFLLLLA 99
            :||..|....|..::||||.||||||:..||:..|.| |:..|||.|||||||.:|.|..||...
Yeast   231 MVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEVALLFYC 295

  Fly   100 LKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVH 164
            ||:.:|:...|.||||||..:.::|||.|||..|| |..::....:.|:.|.|:.:|:.....:|
Yeast   296 LKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKY-SQRIFNMFAQSFESLPLATLINNDYLVMH 359

  Fly   165 GGL--SPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNR 227
            |||  .||.. |...::|||..:.|.||...:|||:||::..|.|.|.||.|:.||.|:..:|.|
Yeast   360 GGLPSDPSAT-LSDFKNIDRFAQPPRDGAFMELLWADPQEANGMGPSQRGLGHAFGPDITDRFLR 423

  Fly   228 TNDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILEL-----------NEYLHR 281
            .|.:..|.|:|:|.|.|.::.....::||:||||||...||:..::.:           |:..:.
Yeast   424 NNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQNL 488

  Fly   282 DFVIFEAAPQESRGIPSKKPQA 303
            ....|||...     |..||.|
Yeast   489 IIETFEAVEH-----PDIKPMA 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_001285489.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	106/267 (40%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	110/282 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810