Protein Alignment Pp4-19C and PPP6C

DIOPT Version :10

• Sequence 1: NP_524803.1
• Gene: Pp4-19C / 45031
• FlyBaseID: FBgn0023177
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_001116827.1
• Gene: PPP6C / 5537
• HGNCID: 9323
• Length: 342
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 183/339 - (53%)
• Similarity: 234/339 - (69%)
• Gaps: 38/339 - (11%)

  Fly     6 DLDRQIEQLKRCEIIKENEVKA-------------------------------------LCAKAR 33
            |||:.:|..:.|:.:.||::|.                                     ||....
Human     5 DLDKYVEIARLCKYLPENDLKVSPICGLAPSGCGAPAGRPFLSPGPPPVFHFLRFLKERLCDYVC 69

  Fly    34 EILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPEKNYLFMGDFVDRGYYSVETFLLLL 98
            ::|:||.|||.|.:|||||||||||||||.|||:.||.||:.||:||||||||||||:|||..||
Human    70 DLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLL 134

  Fly    99 ALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCV 163
            |||.::||||||:|||||||||||||||||||..|||:...|||||::||.|:::|:||.:|.||
Human   135 ALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCV 199

  Fly   164 HGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNRT 228
            ||||||.|:.|||||:|:|.||:||.|..|||:||||||...|.:||||||:|||:.|.::|...
Human   200 HGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHI 264

  Fly   229 NDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILELNEYLHRDFVIFEAAPQES 293
            |::.:||||||||.||:|:.|:|.::||||||||||||||:|:|:...:...|:..:|.|.|...
Human   265 NNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSE 329

  Fly   294 RGIPSKKPQADYFL 307
            |.|| .:....|||
Human   330 RVIP-PRTTTPYFL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_524803.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	176/320 (55%)
PPP6C	NP_001116827.1	MPP_PP2A_PP4_PP6	5..326	CDD:277360	176/320 (55%)