DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pp4-19C and PpD3

DIOPT Version :9

Sequence 1:	NP_001285489.1	Gene:	Pp4-19C / 45031	FlyBaseID:	FBgn0023177	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	331	Identity:	134/331 - (40%)
Similarity:	179/331 - (54%)	Gaps:	37/331 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YSDLDR----------QIEQLK-RCEIIKE-----NEVKALCAK-AREILVEEGNVQR-----VD 46
            |||::.          |:|..| ..:.:||     ...|.|..| |.:||.|.....|     ||
  Fly   186 YSDMENITIEDDYKGPQLEDGKVTLKFMKELMEHYKAQKRLHRKFAYKILCEIDTYMRAQPSLVD 250

  Fly    47 SPV------TVCGDIHGQFYDLKELFKVGGDVPEKN-YLFMGDFVDRGYYSVETFLLLLALKVRY 104
            ..|      |:|||||||||||..:|::.|...||| |||.|||||||.:|||....|...|:.|
  Fly   251 ITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPYLFNGDFVDRGSFSVECIFTLFGFKLLY 315

  Fly   105 PDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGL-S 168
            |:...|.||||||..:.|:|||..|...|| ::|:....|::|::|.|...|:.||..:|||| |
  Fly   316 PNHFFLARGNHESINMNQMYGFTGEVTAKY-TSAMADIFTQVFNWLPLCHCINQKILVMHGGLFS 379

  Fly   169 PSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNRTNDIDM 233
            .....||.||.|:|..:.|.:|.||:||||||:...|.|.|.||.|..||.||..:|.:.|::|.
  Fly   380 TEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMGLGQSKRGVGIQFGPDVTEKFCKDNNLDY 444

  Fly   234 ICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILEL-NEYLHRDFVIFEAAPQESRGIP 297
            |.|:|::...|::...|...:||:||||||...||:.|.:.: ...|..::..|||.|.     |
  Fly   445 IIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGAFITITGNNLKPNYKSFEAVPH-----P 504

  Fly   298 SKKPQA 303
            ..||.|
  Fly   505 DVKPMA 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_001285489.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	127/314 (40%)
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	131/319 (41%)
		PP2Ac	226..502	CDD:197547	120/276 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438821
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740