DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp4-19C and rdgC

DIOPT Version :9

Sequence 1:	NP_001285489.1	Gene:	Pp4-19C / 45031	FlyBaseID:	FBgn0023177	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster

Alignment Length:	324	Identity:	104/324 - (32%)
Similarity:	162/324 - (50%)	Gaps:	30/324 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DYSDLDRQIEQLKRCEIIKENEVKALCAKAREILVEEGNVQ----RVDSPVTVCGDIHGQFYDLK 63
            ::.||...:.:.||...:....|..:..:|.:.|.:..|:.    .|...||||||:||:..||.
  Fly   188 NHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLL 252

  Fly    64 ELFKVGGDVPEKN-YLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFY 127
            .:....|.....| |:|.|||||||...:|..||||:|.:.:|:.:.|.|||||...:...|||.
  Fly   253 VVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFI 317

  Fly   128 DECLRKY--GSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVP--- 187
            .|...||  ....:..:..|::.:|.|.::::.::..||||.|.|.. ||.|:||||.:.|.
  Fly   318 REVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTS-LDLIKSIDRGKYVSILR 381

  Fly   188 ---HDG---------PMCDLLWSDPEDQTGWGVSP---RGAGYLFGSDVVSQFNRTNDIDMICRA 237
               .||         .:.|::||||  |...|..|   ||||..||.||...|.:.:.:..:.|:
  Fly   382 PPLTDGEPLDKTEWQQIFDIMWSDP--QATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRS 444

  Fly   238 HQLVMEGFKWHFNETVLTVWSAPNYCYRCG-NVAAILELNEYLHRDFVIFEAAPQESRGIPSKK 300
            |:....|.::..:..::|::||.|| |..| |..|.:.||..|...||.:.:|..:::.:..|:
  Fly   445 HECKPNGHEFMHDNKIITIFSASNY-YAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQ 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_001285489.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	102/309 (33%)
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	102/309 (33%)
		EFh	616..681	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840