DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp4-19C and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_001285489.1	Gene:	Pp4-19C / 45031	FlyBaseID:	FBgn0023177	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_113715.1	Gene:	Ppp1ca / 24668	RGDID:	3375	Length:	330	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	131/271 - (48%)
Similarity:	192/271 - (70%)	Gaps:	2/271 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPEKNYLFMGDFV 84
            :.|||::.||.|:|||.:.:..:..:::|:.:|||||||:|||..||:.||..||.||||:||:|
  Rat    30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYV 94

  Fly    85 DRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDY 149
            |||..|:||..||||.|::||:...|:|||||...|.::|||||||.|:| :..:|:..|:.|:.
  Rat    95 DRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNC 158

  Fly   150 LSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DQTGWGVSPRGA 213
            |.::||:|.||||.||||||.:|.::|||.|.|..:||..|.:||||||||: |..|||.:.||.
  Rat   159 LPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGV 223

  Fly   214 GYLFGSDVVSQFNRTNDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILELNEY 278
            .:.||::||::|...:|:|:||||||:|.:|:::.....::|::||||||....|..|::.::|.
  Rat   224 SFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 288

  Fly   279 LHRDFVIFEAA 289
            |...|.|.:.|
  Rat   289 LMCSFQILKPA 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_001285489.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	131/271 (48%)
Ppp1ca	NP_113715.1	MPP_PP1_PPKL	8..298	CDD:277359	130/268 (49%)
Ppp1ca	NP_113715.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820