DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp4-19C and R08C7.8

DIOPT Version :9

Sequence 1:	NP_001285489.1	Gene:	Pp4-19C / 45031	FlyBaseID:	FBgn0023177	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_500563.2	Gene:	R08C7.8 / 177208	WormBaseID:	WBGene00019951	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	104/334 - (31%)
Similarity:	164/334 - (49%)	Gaps:	43/334 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RQIEQLKR---CEIIKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGG 70
            |.||.|.:   .:...:.::..:..||...|.....:.:|:.|:|:.||||||...|...|...|
Worm    13 RMIEHLLKWGVTDAFTDKQIYTILEKAESTLKPLPAMLQVEHPITIVGDIHGQLDALIRYFDAVG 77

  Fly    71 DVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYG 135
            ..|:..:||:||:||||..|.|..|||...|:|||..:.|:|||||..::.::||||:|..||.|
Worm    78 YPPKVQFLFLGDYVDRGAKSFEVSLLLFCYKIRYPHLVHLLRGNHECMKMNRLYGFYEELTRKRG 142

  Fly   136 STAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVP---HDGPMCDLLW 197
            . .:||....:|:.|.|.|.:..:|.|:|||:|.:....:..::: :|...|   .:|...||:|
Worm   143 G-RMWRQYQNVFNELPLCARVGQRILCMHGGISQNCNSWESFKAL-KKPNTPLTCDEGLQVDLMW 205

  Fly   198 SDP-EDQTGWGV--SPRGAGYLFGSDVVSQFNRTNDIDMICRAHQLVMEGFKWHFNETVLTVWSA 259
            :|| :|:.....  ..|....:||...:..|.:...:.:|.|||::..|||.:.||:..:||:||
Worm   206 ADPTQDKCNTFAMNKQRAISVVFGQKGLDDFLKKLGLSLIVRAHEVSQEGFNFLFNKKCVTVFSA 270

  Fly   260 PNYCYRCGNVAAILELNEYLHRDFVI-----------FE--------------AAPQESRG---- 295
            |.||....|..||:.:::.....|.:           ||              |:|..:||
Worm   271 PYYCGNDTNCGAIMHVSDSYELSFTVLRPRMIATPENFEIVKLMENNYKGLMVASPDPNRGRHLQ 335

  Fly   296 ---IPSKKP 301
               :|...|
Worm   336 SADVPQPTP 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_001285489.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	99/314 (32%)
R08C7.8	NP_500563.2	PP2Ac	27..299	CDD:197547	92/273 (34%)
R08C7.8	NP_500563.2	MPP_PPP_family	57..286	CDD:277316	86/230 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820