DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp4-19C and pph-4.1

DIOPT Version :9

Sequence 1:	NP_001285489.1	Gene:	Pp4-19C / 45031	FlyBaseID:	FBgn0023177	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_499603.1	Gene:	pph-4.1 / 176657	WormBaseID:	WBGene00004085	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	242/303 - (79%)
Similarity:	271/303 - (89%)	Gaps:	1/303 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DLDRQIEQLKRCEIIKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGG 70
            ||||.||:|.|||:|.|.:||.|||||||||.||||||.:|||||:|||||||||||.|||||||
Worm    31 DLDRHIEKLMRCELIAEQDVKTLCAKAREILAEEGNVQVIDSPVTICGDIHGQFYDLMELFKVGG 95

  Fly    71 DVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYG 135
            .||..||||:|||||||:|||||||||||||.|||||:.||||||||||||||||||||||||||
Worm    96 PVPNTNYLFLGDFVDRGFYSVETFLLLLALKARYPDRMMLIRGNHESRQITQVYGFYDECLRKYG 160

  Fly   136 STAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDP 200
            :.:||::|||:||||||:|:||||:|||||||||||..:||||.|||||||||||||||||||||
Worm   161 NASVWKHCTEVFDYLSLAAVIDGKVFCVHGGLSPSISTMDQIRVIDRKQEVPHDGPMCDLLWSDP 225

  Fly   201 ED-QTGWGVSPRGAGYLFGSDVVSQFNRTNDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCY 264
            |: ..|||:||||||||||:|....|..||.:|:|||||||||||:||||||.||||||||||||
Worm   226 EEGNVGWGLSPRGAGYLFGADASKTFCETNGVDLICRAHQLVMEGYKWHFNEKVLTVWSAPNYCY 290

  Fly   265 RCGNVAAILELNEYLHRDFVIFEAAPQESRGIPSKKPQADYFL 307
            |||||||||||:|.|:::|.||||||||:||.|:|||.|||||
Worm   291 RCGNVAAILELDENLNKEFTIFEAAPQENRGAPAKKPHADYFL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp4-19C	NP_001285489.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	227/284 (80%)
pph-4.1	NP_499603.1	PTZ00239	31..333	CDD:173488	240/301 (80%)
pph-4.1	NP_499603.1	MPP_PP2A_PP4_PP6	31..316	CDD:277360	227/284 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161933
Domainoid	1	1.000	342	1.000	Domainoid score	I570
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2038
Inparanoid	1	1.050	525	1.000	Inparanoid score	I674
Isobase	1	0.950	-	0	Normalized mean entropy	S105
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D349967at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		oto20395
orthoMCL	1	0.900	-	-		OOG6_101963
Panther	1	1.100	-	-	LDO	PTHR45619
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1992
SonicParanoid	1	1.000	-	-		X1987
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750