Protein Alignment Zfrp8 and PDCD2

DIOPT Version :10

• Sequence 1: NP_611890.1
• Gene: Zfrp8 / 45021
• FlyBaseID: FBgn0021875
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_002589.2
• Gene: PDCD2 / 5134
• HGNCID: 8762
• Length: 344
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 143/358 - (39%)
• Similarity: 192/358 - (53%)
• Gaps: 45/358 - (12%)

  Fly     3 IDLGFAEKSDNGAW-LSNRYFPSKLGGQPAWLELEALPPTSQLQCSKCRAPKSFLAQLYAPFEDE 66
            ::|||||.:.  || |.:..||||:||:||||....||....|.|..|..|.|||.|:|||....
Human     9 VELGFAESAP--AWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSFLLQVYAPLPGR 71

  Fly    67 YN-FHRSIYVFLCRNSDCQEAQNASNFTVLRSQLPRKNKFFSEEEPSDVGQPLPAV---PCLK-- 125
            .: |||.|::|.||...|     .:...|.|:||||||.|:|.|.||:  .|.|..   .||:
Human    72 PDAFHRCIFLFCCREQPC-----CAGLRVFRNQLPRKNDFYSYEPPSE--NPPPETGESVCLQLK 129

  Fly   126 ---KLCAACGCHAPHACSKCKAIHYCSPEHQRAHWP-QHKPNCGAPEVATE-KPLTQIVFPEFEI 185
               .||..|||..|..||:|...:|||.|||...|. .||..|..|:.... .|....:||||||
Human   130 SGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEI 194

  Fly   186 VMDSNPVESGEEDKDDEARLAEFQELESSGKTGDLSNVSEAEMDKYFGNSAAADDKTFRQFKKQT 250
            |     :|:.:|...:.....::.|:     .|.:....|.|:|. .....:.:||.|::||.|.
Human   195 V-----IETEDEIMPEVVEKEDYSEI-----IGSMGEALEEELDS-MAKHESREDKIFQKFKTQI 248

  Fly   251 AAEPDQIVRYKRGGQPLWITNTVKTVED--QLNKLPNCIACGGERQFEFQIMPQALTLLEDENL- 312
            |.||:||:||.||..|:||:.     |:  |...:|:| .||.:|..|||:|||.|..|:.:.|
Human   249 ALEPEQILRYGRGIAPIWISG-----ENIPQEKDIPDC-PCGAKRILEFQVMPQLLNYLKADRLG 307

  Fly   313 ---DWGVLAVYTCAKSCPI-DGYVEELLIKQDI 341
               |||:|||:|||:||.: .||.||.:.|||:
Human   308 KSIDWGILAVFTCAESCSLGTGYTEEFVWKQDV 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zfrp8	NP_611890.1	zf-MYND	128..164	CDD:460312	17/36 (47%)
		PDCD2_C	240..340	CDD:461221	50/106 (47%)
PDCD2	NP_002589.2	zf-MYND	135..172	CDD:460312	17/36 (47%)
		PDCD2_C	238..339	CDD:461221	50/106 (47%)