DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zfrp8 and trus

DIOPT Version :9

Sequence 1:	NP_001286828.1	Gene:	Zfrp8 / 45021	FlyBaseID:	FBgn0021875	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_650205.1	Gene:	trus / 41540	FlyBaseID:	FBgn0038055	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	484	Identity:	99/484 - (20%)
Similarity:	158/484 - (32%)	Gaps:	188/484 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SKLGGQPAWLELEALPPTSQLQCSKCRAPKSFLAQLYAPFEDEYNFHRSIYVFLCRNSDCQEAQN 88
            :|:||.|.|...|...|:    |..|.|.:..:.|:|||. |...||||:|||.|.|..|  :||
  Fly    30 NKIGGTPDWPRHEVTIPS----CPLCGAVRPLIVQMYAPL-DRSQFHRSLYVFGCMNPVC--SQN 87

  Fly    89 ASNFTVLRSQ-LPRKNKFFSEEEPSDVGQPLPAVPC----LKKLCAACGCHAPHACS-------- 140
            :.::..:|:| |..:.:..||..|.       |.|.    .||...:.|..|...||
  Fly    88 SKSWCCVRTQHLDHQYEVISEHSPK-------ATPTKKQNSKKKGKSSGLQAISWCSGADDWGDS 145

  Fly   141 ----------------------------------KCKAIHYCSPEHQ---RAHWPQ--------- 159
                                              :..|:.|...:.|   .|...|
  Fly   146 SGGATEQAKTISVALDEAMDITADDDQNERNGNVRPNALQYAKSDIQIDEPAKLEQVKIAADDDD 210

  Fly   160 ----------------HKPNCGAPEVATEKPL------------------------TQIVFPEFE 184
                            |:.:..:|:.|.:.|.                        .:|..||.:
  Fly   211 DEDESTSLENELISGFHQMDMISPQNADDDPNANCAAAAAPSLDGAGASAASAAIGAEIEGPETD 275

  Fly   185 IVMDSNPVESGEED-----KDDEARLAEFQE--LESSGKTGDLSNVSEAEMDKYFGNSAAAD--- 239
            :|:...| :..|.|     |.....|::.::  |:|.....|:.|.::||..:.||.:.:.|
  Fly   276 LVLVDTP-KKPERDLIALLKHTSGALSQIKDLTLKSYYIAVDVENKTQAEEYENFGGALSMDHIR 339

  Fly   240 ------------------------------------------DKTFRQFKKQTAAEPDQIVRYKR 262
                                                      |..|..|.......|.|::||.|
  Fly   340 DLYQEYKLRDQNPGQSPTGGASGPGEQGDENESYEKALPAHGDLVFHNFITTIHQNPGQLLRYSR 404

  Fly   263 GGQPLWITNTVKTVEDQLNKLPNCIACGGERQFEFQIMPQALTLLE------DENLDWGVLAVYT 321
            ...||.:....:       .||.|..|.||...|.|::|..:..|.      :..:::|.:.|:|
  Fly   405 DTIPLLVAPFTE-------PLPKCQNCRGETICEVQLLPTLIPKLRFQVNGCNAPIEFGNVLVFT 462

  Fly   322 CAKSC---PIDGYVEELLIKQDIVAEDQS 347
            |.|||   |      :|:..:.||.:.::
  Fly   463 CLKSCWDTP------DLMRYEHIVVQSET 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zfrp8	NP_001286828.1	zf-MYND	128..164	CDD:280009	10/105 (10%)
Zfrp8	NP_001286828.1	PDCD2_C	238..340	CDD:282100	30/155 (19%)
trus	NP_650205.1	PDCD2_C	371..482	CDD:282100	31/123 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456792
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3310
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1181470at2759
OrthoFinder	1	1.000	-	-		FOG0001596
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1686
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.730