DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zfrp8 and SMYD1

DIOPT Version :9

Sequence 1:	NP_001286828.1	Gene:	Zfrp8 / 45021	FlyBaseID:	FBgn0021875	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_938015.1	Gene:	SMYD1 / 150572	HGNCID:	20986	Length:	490	Species:	Homo sapiens

Alignment Length:	127	Identity:	32/127 - (25%)
Similarity:	46/127 - (36%)	Gaps:	34/127 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 CHA-------PHACSKCKAIHYCSPEHQRAHWPQHKPNCGAPEVATEKPLTQIVFPEFEIVMDSN 190
            ||.       .|.|.:||..|||....|:..|..||..|.|.:...:.|
Human    52 CHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGKVP---------------- 100

  Fly   191 PVESGEEDKDDEARLAEFQELESSGKT-GDLSNVSEAEMD-KYFGNSAAADDK----TFRQF 246
                 .|:....||:....|.|.:|.| |.|.:|.:.:.. ::||.....|.:    ||.|:
Human   101 -----NENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQY 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zfrp8	NP_001286828.1	zf-MYND	128..164	CDD:280009	13/37 (35%)
Zfrp8	NP_001286828.1	PDCD2_C	238..340	CDD:282100	4/13 (31%)
SMYD1	NP_938015.1	S-adenosyl-L-methionine binding. /evidence=ECO:0000250	17..19
		zf-MYND	52..90	CDD:307734	13/37 (35%)
		SET	<194..257	CDD:214614
		S-adenosyl-L-methionine binding. /evidence=ECO:0000250	205..206
		S-adenosyl-L-methionine binding. /evidence=ECO:0000250	270..272
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000