Protein Alignment Vha68-2 and atp6v1aa

DIOPT Version :10

• Sequence 1: NP_652004.2
• Gene: Vha68-2 / 45012
• FlyBaseID: FBgn0263598
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_957429.1
• Gene: atp6v1aa / 394110
• ZFINID: ZDB-GENE-040426-1143
• Length: 617
• Species: Danio rerio
• Alignment Length: 614
• Identity: 513/614 - (83%)
• Similarity: 568/614 - (92%)
• Gaps: 1/614 - (0%)

  Fly     2 SNLKRFDDEERESKYGRVFAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYE 66
            |.|.:..||||||::|.|..||||||||.:|:|:|||||||||:.||||||||||||||||||||
Zfish     4 SKLPKIRDEERESQFGYVHGVSGPVVTASSMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYE 68

  Fly    67 ETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINELTESIYIPKGVNVPSLSRVASW 131
            |||||.||||||||||||||||||||||||||||||||||||:||:|||||:|||:.:|:|...|
Zfish    69 ETSGVCVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINDLTQSIYIPRGVNIGALNRDLKW 133

  Fly   132 EFNPL-NVKVGSHITGGDLYGLVHENTLVKHKMIVNPRAKGTVRYIAPSGNYKVDDVVLETEFDG 195
            :|.|: |::||||:||||:||||:||:|:|||:::.||::|||.|:||.|||.|.|||||.||:|
Zfish   134 DFTPINNLRVGSHVTGGDIYGLVNENSLIKHKLMLPPRSRGTVTYVAPPGNYDVSDVVLELEFEG 198

  Fly   196 EITKHTMLQVWPVRQPRPVTEKLPANHPLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQAL 260
            ...|.||:|||||||.|||||||||||||||||||||:|||||||||||||||||||||||||:|
Zfish   199 VKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSL 263

  Fly   261 SKYSNSDVIIYVGCGERGNEMSEVLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIY 325
            |||||||||||||||||||||||||||||||::|:.|..||||||||||||||||||||||||||
Zfish   264 SKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVGGKVESIMKRTALVANTSNMPVAAREASIY 328

  Fly   326 TGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVK 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   329 TGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVK 393

  Fly   391 CLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYM 455
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||.
Zfish   394 CLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYT 458

  Fly   456 RALDDFYDKNFPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQN 520
            ||||::|||:|.||||||||.|||||.||||:||||||||||||||||||||||||:||||||||
Zfish   459 RALDEYYDKHFQEFVPLRTKAKEILQGEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQN 523

  Fly   521 SYSSYDRFCPFYKTVGMLRNIIDFYDMARHSVESTAQSENKITWNVIREAMGNIMYQLSSMKFKD 585
            .|:.||||||||||||:|.|:|.|||:|||:||:||||:|||||..|||.||.|:|::|||||||
Zfish   524 GYTPYDRFCPFYKTVGILSNMIAFYDLARHAVETTAQSDNKITWAQIREHMGEILYRISSMKFKD 588

  Fly   586 PVKDGEAKIKADFEQLHEDLQQAFRNLED 614
            |||:||||||||:.||.||:|.:||.|||
Zfish   589 PVKEGEAKIKADYAQLLEDMQNSFRTLED 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-2	NP_652004.2	V-ATPase_V1_A	16..606	CDD:273411	499/590 (85%)
atp6v1aa	NP_957429.1	V-ATPase_V1_A	17..609	CDD:273411	499/591 (84%)