Protein Alignment Vha68-2 and Atp6v1a

DIOPT Version :10

• Sequence 1: NP_652004.2
• Gene: Vha68-2 / 45012
• FlyBaseID: FBgn0263598
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_031534.2
• Gene: Atp6v1a / 11964
• MGIID: 1201780
• Length: 617
• Species: Mus musculus
• Alignment Length: 614
• Identity: 514/614 - (83%)
• Similarity: 566/614 - (92%)
• Gaps: 1/614 - (0%)

  Fly     2 SNLKRFDDEERESKYGRVFAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYE 66
            |.|.:..||::||.:|.|..||||||||..|:|:|||||||||:.||||||||||||||||||||
Mouse     4 SKLPKIRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYE 68

  Fly    67 ETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINELTESIYIPKGVNVPSLSRVASW 131
            |||||:||||||||||||||||||||||:|||||||||.||:..|:|||||:||||.:|||...|
Mouse    69 ETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKW 133

  Fly   132 EFNP-LNVKVGSHITGGDLYGLVHENTLVKHKMIVNPRAKGTVRYIAPSGNYKVDDVVLETEFDG 195
            ||.| .|::|||||||||:||:|:||:|:|||:::.||.:|:|.||||.|||...|||||.||:|
Mouse   134 EFIPSKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTYIAPPGNYDASDVVLELEFEG 198

  Fly   196 EITKHTMLQVWPVRQPRPVTEKLPANHPLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQAL 260
            ...|.:|:|||||||.|||||||||||||||||||||:|||||||||||||||||||||||||:|
Mouse   199 VKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSL 263

  Fly   261 SKYSNSDVIIYVGCGERGNEMSEVLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIY 325
            |||||||||||||||||||||||||||||||::|:||..||||||||||||||||||||||||||
Mouse   264 SKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIY 328

  Fly   326 TGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVK 390
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   329 TGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVK 393

  Fly   391 CLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYM 455
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||
Mouse   394 CLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM 458

  Fly   456 RALDDFYDKNFPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQN 520
            ||||::|||:|.||||||||.||||||||||:||||||||||||||||||||||||:||||||||
Mouse   459 RALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQN 523

  Fly   521 SYSSYDRFCPFYKTVGMLRNIIDFYDMARHSVESTAQSENKITWNVIREAMGNIMYQLSSMKFKD 585
            .|:.||||||||||||||.|:|.||||||.:||:||||:|||||::|||.||.|:|:||||||||
Mouse   524 GYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKD 588

  Fly   586 PVKDGEAKIKADFEQLHEDLQQAFRNLED 614
            ||||||||||||:.||.||:|.|||:|||
Mouse   589 PVKDGEAKIKADYAQLLEDMQNAFRSLED 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-2	NP_652004.2	V-ATPase_V1_A	16..606	CDD:273411	501/590 (85%)
Atp6v1a	NP_031534.2	V-ATPase_V1_A	17..609	CDD:273411	501/591 (85%)