DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tom40 and tomboy40

DIOPT Version :9

Sequence 1:	NP_001259313.1	Gene:	Tom40 / 44978	FlyBaseID:	FBgn0016041	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_610213.1	Gene:	tomboy40 / 35553	FlyBaseID:	FBgn0033074	Length:	340	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	238/345 - (68%)
Similarity:	278/345 - (80%)	Gaps:	6/345 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNVLAASSGAPGS-GASNLGLGLQEPAPLPSNSGSLTESSSSAEGLDSLAAAKDAALENPGTVE 64
            ||||:|:::.|..| |..:|..||:.| ..|..||.:  .....|.|.  |.||...|.||||:|
  Fly     1 MGNVMASTADAESSRGRGHLSAGLRLP-EAPQYSGGV--PPQMVEALK--AEAKKPELTNPGTLE 60

  Fly    65 ELHKKCKDIQAITFEGAKIMLNKGLSNHFQVSHTINMSNVVPSGYRFGATYVGTKEFSPTEAFPV 129
            |||.:|:||||.||||||||:||||||||||:|||||::..||||||||||||||::.|||||||
  Fly    61 ELHSRCRDIQANTFEGAKIMVNKGLSNHFQVTHTINMNSAGPSGYRFGATYVGTKQYGPTEAFPV 125

  Fly   130 LLGDIDPAGNLNANVIHQFSARLRCKFASQIQESKVVASQLTTDYRGSDYTLSLTVANPSIFTNS 194
            |||:|||.||||||||||.::|||||||||.|:||:|.:|||.||||.||||:||:.||..||:|
  Fly   126 LLGEIDPMGNLNANVIHQLTSRLRCKFASQFQDSKLVGTQLTGDYRGRDYTLTLTMGNPGFFTSS 190

  Fly   195 GVVVGQYLQSVTPALALGSELAYQFGPNVPGRQIAIMSVVGRYTAGSSVWSGTLGQSGLHVCYYQ 259
            ||.|.|||||||..||||||.||.:||||||||:|::|.||||..|.:|||.|||.:|.|:.|||
  Fly   191 GVFVCQYLQSVTKRLALGSEFAYHYGPNVPGRQVAVLSAVGRYAFGDTVWSCTLGPAGFHLSYYQ 255

  Fly   260 KASDQLQIGAEVETSLRMQESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRLAPLPFTLAL 324
            |||||||||.||||::|.|||.||:|||||||||:|||||.:||||.|.|||||||.||||:||:
  Fly   256 KASDQLQIGVEVETNIRQQESTATVAYQIDLPKADLVFRGSLDSNWLISGVLEKRLQPLPFSLAI 320

  Fly   325 SGRMNHVKNNFRLGCGLMIG 344
            ||||||.||:||||||||||
  Fly   321 SGRMNHQKNSFRLGCGLMIG 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tom40	NP_001259313.1	Porin3_Tom40	57..344	CDD:132766	216/286 (76%)
tomboy40	NP_610213.1	Porin3_Tom40	53..340	CDD:132766	216/286 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463704
Domainoid	1	1.000	97	1.000	Domainoid score	I2428
eggNOG	1	0.900	-	-		E1_KOG3296
Homologene	1	1.000	-	-		H101105
Inparanoid	1	1.050	102	1.000	Inparanoid score	I2156
Isobase	1	0.950	-	0	Normalized mean entropy	S1946
OMA	1	1.010	-	-		QHG55758
OrthoDB	1	1.010	-	-		D1346842at2759
OrthoFinder	1	1.000	-	-		FOG0001620
OrthoInspector	1	1.000	-	-		mtm6454
orthoMCL	1	0.900	-	-		OOG6_101593
Panther	1	1.100	-	-	P	PTHR10802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1729
	14	13.760