DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer2LCH and Ripor2

DIOPT Version :9

Sequence 1:	NP_001263106.1	Gene:	Fer2LCH / 44965	FlyBaseID:	FBgn0015221	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001014031.2	Gene:	Ripor2 / 306934	RGDID:	1306939	Length:	1310	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	62/244 - (25%)
Similarity:	89/244 - (36%)	Gaps:	59/244 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ACLGSLALAKDDE------YCQN---TVITACSTSAFSALTGFFTGKTNSICNARFAGIDHIEPE 66
            |||...:|...:.      .||:   .:.|..|.:..|......:..|:.|   |......:|..
  Rat  1105 ACLALKSLEATESIKMLVTLCQSDTEEIRTVASETLLSLAPYSGSAMTSQI---RQNYSTEVEAA 1166

  Fly    67 IQSYINANLAKSYDYLLLATHFNSYQKNRPGFQKLYQGLSDRSFEDSIALIKQVTRRGGIVDFNT 131
            :...:|.:|..||.||.|...|:                     .|.:||  :...|||...|..
  Rat  1167 VNRLVNLHLRASYTYLSLGFFFD---------------------PDDVAL--EGNERGGRALFQD 1208

  Fly   132 RHESSGSVSTKRGTLEVDELHSLALALDTEKQLATGATHVHSRATHATDAERDPELAHYFEENFL 196
            ..:.|.....|  |||..|   .||||  ||.|......:|:..:    |..||.|..:.|.:||
  Rat  1209 VQKPSQDEWGK--TLEAME---AALAL--EKNLNQALLDLHALGS----ARTDPHLCDFLESHFL 1262

  Fly   197 GKQAESVRKLSGYANDLAKLMKVPDP----------SLSVYLFDEYLQK 235
            .|:.:.::|:   .|.|..|.:|..|          ||..|||:....|
  Rat  1263 DKEVKLIKKM---GNHLTNLRRVAGPQPAQTGVAQASLGEYLFERLTLK 1308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer2LCH	NP_001263106.1	Euk_Ferritin	60..232	CDD:153114	49/181 (27%)
Ripor2	NP_001014031.2	PL48	118..529	CDD:292525
		Involved in cell filopodia formation. /evidence=ECO:0000250\|UniProtKB:Q9Y4F9	196..254
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	588..639
		PI-PLCc_GDPD_SF	<963..>1097	CDD:301322
		Ferritin_like	1160..1304	CDD:294190	49/180 (27%)
		Ferritin	1164..1282	CDD:278632	42/154 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810