Protein Alignment Actn3 and Smtnl2

DIOPT Version :10

• Sequence 1: NP_524801.1
• Gene: Actn3 / 44964
• FlyBaseID: FBgn0015008
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_808444.1
• Gene: Smtnl2 / 276829
• MGIID: 2442764
• Length: 456
• Species: Mus musculus
• Alignment Length: 465
• Identity: 90/465 - (19%)
• Similarity: 166/465 - (35%)
• Gaps: 117/465 - (25%)

  Fly   156 QRAAENRLAEKQDRIKALEECLANCKFQLKNVNEQYQKLKKASNQLIRESNQIR----------- 209
            ||..|.|:||    ...|...||....:|:..|::.|.      ||.|.:.|:.
Mouse    39 QRGVERRVAE----ALRLAGPLARTVAELQRDNQRLQA------QLERLTRQVEALGLATGVSPA 93

  Fly   210 ---PQKSWSVLVGRRKGRISTRTSFVWKSLKLDQSERETLMGLKKRLSEEKEIKLRAKTEMSKIR 271
               |....:..|..|..|:.|        .:.......:|.|....:..::...|       ::|
Mouse    94 PGTPSPPPAATVTDRAPRLGT--------ARFSSHATFSLSGRSPSVEHDEASDL-------EVR 143

  Fly   272 KAMDELCLGKG-ELQFGLQNKS---ETDASKDTLVVIDKALSALSQYNTLKFPDCNFQLSRLMKS 332
            :|.:...|..| :|..|..|.|   :|.::::.......:||.                 |:...
Mouse   144 RASNSCILENGHQLDAGPANGSSEVQTSSAQEPPRPRPVSLSL-----------------RMPHQ 191

  Fly   333 LYGSLTTIRDRWIRKIS-SAVEP---------TPSCLKSNTPSLPEPPLTVSFSTDLFWDKIYKP 387
            ...::|.:.:::..:.| ||:.|         |||..::.:|..|.|....|..|.......|..
Mouse   192 PVTAVTRVSEKFSGETSASALSPTSAAIVGGFTPSPSEAISPWTPSPTEKSSSFTRSLSGSGYGA 256

  Fly   388 CT----QSNPVMPNTSLIPVLPKKQPKSLQLTCEPSVQYKVASRSSTTAPVPKYLG--------- 439
            .|    :.:|.:......|  |..||.::........:.:...||.|   :|:..|
Mouse   257 VTAGKRKDSPPLVTPPQSP--PSSQPPAMTQAPRQGERRRELVRSQT---LPRTSGAQARKALFE 316

  Fly   440 ---------------------KTFGDRRLS-----LLRWCQERVKPY-GIPMYEFSASWISGRAL 477
                                 ::||....|     ||.||:.:...| .:.:..||:||..|.|.
Mouse   317 KWEQDTASKGKGETRAKLKRSQSFGVASASSIKQILLEWCRSKTVGYQHVDLQNFSSSWSDGMAF 381

  Fly   478 CAIIHSYLPDLIDKTYLAKKKPEEVLAYGIKVAKSIGVSDSVDLIRELR-QGR-PNLEKIVDFVE 540
            ||::||:.||..|...|:..:.::.......:|:::...:.:..:.::. .|| |:...:..:|:
Mouse   382 CALVHSFFPDAFDYNALSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQ 446

  Fly   541 ELQGYLDMYD 550
            .|..:|..::
Mouse   447 SLYNHLRRFE 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn3	NP_524801.1	SMC_N	<13..277	CDD:481474	26/134 (19%)
		CH_SF	443..540	CDD:469584	25/104 (24%)
Smtnl2	NP_808444.1	PRK09039	<8..>84	CDD:181619	16/54 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..140		2/19 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..190		9/52 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..310		20/94 (21%)
		CH_SMTNL2	347..453	CDD:409110	25/105 (24%)